Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyWinged helix DNA-binding domain 8002723 3000034 SCOP2B (2022-06-29)
ASCOP2B SuperfamilycAMP-binding domain-like 8002726 3000084 SCOP2B (2022-06-29)
BSCOP2B SuperfamilycAMP-binding domain-like 8002726 3000084 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyWinged helix DNA-binding domain 8002723 3000034 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AcNMP_bindinge3fweA1 A: beta sandwichesX: jelly-rollH: Double-stranded beta-helix (From Topology)T: Double-stranded beta-helixF: cNMP_bindingECOD (1.6)
ACrpe3fweA2 A: alpha arraysX: HTHH: HTHT: wingedF: CrpECOD (1.6)
BcNMP_bindinge3fweB1 A: beta sandwichesX: jelly-rollH: Double-stranded beta-helix (From Topology)T: Double-stranded beta-helixF: cNMP_bindingECOD (1.6)
BCrpe3fweB2 A: alpha arraysX: HTHH: HTHT: wingedF: CrpECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

AMR Gene: CARD Annotation CARD Database Homepage

ChainsAccessionShort NameDescriptionProvenance Source (Version)
A, B
ARO:3000518CRPCRP is a global regulator that represses MdtEF multidrug efflux pump expression.CARD (3.3.0)

AMR Gene Family: CARD Annotation CARD Database Homepage

ChainsAccessionGene FamilyDrug Class Resistance MachanismProvenance Source (Version)
A, B
ARO:0010004resistance-nodulation-cell division (RND) antibiotic efflux pumpmacrolide antibiotic, fluoroquinolone antibiotic, penamantibiotic effluxCARD (3.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF13545Crp-like helix-turn-helix domain (HTH_Crp_2)Crp-like helix-turn-helix domainThis family represents a crp-like helix-turn-helix domain that is likely to bind DNA.Domain
A, B
PF00027Cyclic nucleotide-binding domain (cNMP_binding)Cyclic nucleotide-binding domainThis domain sensor domain can bind cAMP, cGMP, c-di-GMP, oxygen and 2-oxoglutarate (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
Catabolite gene activator