Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2 FamilyHeme-binding protein A (HasA) 8085665 4001106 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyHeme-binding protein A (HasA) 8085666 3000777 SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AHasAe3w8mA1 A: a+b two layersX: Heme-binding protein A (HasA) (From Topology)H: Heme-binding protein A (HasA) (From Topology)T: Heme-binding protein A (HasA)F: HasAECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.30.1500.10 Alpha Beta 2-Layer Sandwich Heme-binding Protein A Chain: ACATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF06438Heme-binding protein A (HasA) (HasA)Heme-binding protein A (HasA)Free iron is limited in vertebrate hosts, thus an alternative to siderophores has been developed by pathogenic bacteria to access host iron bound in protein complexes. HasA is a secreted hemophore that has the ability to obtain iron from hemoglobin. ...Free iron is limited in vertebrate hosts, thus an alternative to siderophores has been developed by pathogenic bacteria to access host iron bound in protein complexes. HasA is a secreted hemophore that has the ability to obtain iron from hemoglobin. Once bound to HasA, the heme is shuttled to the receptor HasR, which releases the heme into the bacterium [1].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Heme acquisition protein HasAp - -

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
IPR010495Haem-binding HasAFamily
IPR036912Haem-binding HasA superfamilyHomologous Superfamily