Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyNucleotide cyclase/DNA polymerase palm domain-like 8037492 3001272 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyNucleotide cyclase/DNA polymerase palm domain-like 8037492 3001272 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyRibonuclease H-like 8044539 3000143 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ADNA_pol_A_2nde4bwjA1 A: alpha arraysX: helical bundle in Bacillus stearothermophilus-like DNA polymerase I (From Topology)H: helical bundle in Bacillus stearothermophilus-like DNA polymerase I (From Topology)T: helical bundle in Bacillus stearothermophilus-like DNA polymerase IF: DNA_pol_A_2ndECOD (1.6)
ADNA_pol_A_1ste4bwjA2 A: alpha bundlesX: fingers domain in bacteriophage RB69-like DNA polymerase I (From Topology)H: fingers domain in bacteriophage RB69-like DNA polymerase I (From Topology)T: fingers domain in bacteriophage RB69-like DNA polymerase IF: DNA_pol_A_1stECOD (1.6)
ADNA_pol_A_3rde4bwjA3 A: a+b two layersX: Alpha-beta plaitsH: Adenylyl and guanylyl cyclase catalytic domain-likeT: Adenylyl and guanylyl cyclase catalytic domain-likeF: DNA_pol_A_3rdECOD (1.6)
ATaq-exonuce4bwjA4 A: mixed a+b and a/bX: Ribonuclease H-likeH: Ribonuclease H-like (From Topology)T: Ribonuclease H-likeF: Taq-exonucECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.30.420.10 Alpha Beta 2-Layer Sandwich Nucleotidyltransferase domain 5CATH (4.3.0)
A1.20.1060.10 Mainly Alpha Up-down Bundle Taq DNA Polymerase Chain T, domain 4CATH (4.3.0)
A3.30.70.370 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits CATH (4.3.0)
A1.10.150.20 Mainly Alpha Orthogonal Bundle DNA polymerase domain 1CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF09281Taq polymerase, exonuclease (Taq-exonuc)Taq polymerase, exonucleaseMembers of this family are found in prokaryotic Taq DNA polymerase, where they assume a ribonuclease H-like motif. The domain confers 5'-3' exonuclease activity to the polymerase [1].Domain
PF00476DNA polymerase family A (DNA_pol_A)DNA polymerase family A- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
DNA POLYMERASE I, THERMOSTABLE -
5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*DOCP)-3'---
5'-D(*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*CP)-3'---