Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilySimibi-like P-loop NTPases 8091490 3002018 SCOP2B (2022-06-29)
ASCOP2B SuperfamilycAMP-binding domain-like 8091491 3000084 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyClp1 C-terminal domain-like 8091489 3002513 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyClp1 C-terminal domain-like 8091489 3002513 SCOP2B (2022-06-29)
BSCOP2B SuperfamilycAMP-binding domain-like 8091491 3000084 SCOP2B (2022-06-29)
BSCOP2B SuperfamilySimibi-like P-loop NTPases 8091490 3002018 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AClp1e4c0hA1 A: beta barrelsX: Protein CLP1 C-terminal domain (From Topology)H: Protein CLP1 C-terminal domain (From Topology)T: Protein CLP1 C-terminal domainF: Clp1ECOD (1.6)
ACLP1_N_1e4c0hA3 A: beta sandwichesX: jelly-rollH: Protein CLP1 jelly-roll domain (From Topology)T: Protein CLP1 jelly-roll domainF: CLP1_N_1ECOD (1.6)
ACLP1_Pe4c0hA2 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: CLP1_PECOD (1.6)
BClp1e4c0hB1 A: beta barrelsX: Protein CLP1 C-terminal domain (From Topology)H: Protein CLP1 C-terminal domain (From Topology)T: Protein CLP1 C-terminal domainF: Clp1ECOD (1.6)
BCLP1_N_1e4c0hB3 A: beta sandwichesX: jelly-rollH: Protein CLP1 jelly-roll domain (From Topology)T: Protein CLP1 jelly-roll domainF: CLP1_N_1ECOD (1.6)
BCLP1_Pe4c0hB2 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: CLP1_PECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF06807Pre-mRNA cleavage complex II protein Clp1 (Clp1)Pre-mRNA cleavage complex II protein Clp1- Family
A, B
PF16573N-terminal beta-sandwich domain of polyadenylation factor (CLP1_N)N-terminal beta-sandwich domain of polyadenylation factor- Family
A, B
PF16575mRNA cleavage and polyadenylation factor CLP1 P-loop (CLP1_P)mRNA cleavage and polyadenylation factor CLP1 P-loopCLP1_P is the P-loop carrying domain of Clp1 mRNA cleavage and polyadenylation factor, Clp1, proteins in eukaryotes. Clp1 is essential for 3'-end processing of mRNAs. This region carries the P-loop suggesting it is the region that binds adenine or g ...CLP1_P is the P-loop carrying domain of Clp1 mRNA cleavage and polyadenylation factor, Clp1, proteins in eukaryotes. Clp1 is essential for 3'-end processing of mRNAs. This region carries the P-loop suggesting it is the region that binds adenine or guanine nucleotide [1].
Domain
C, D
PF11526Pcf11, Clp1-interaction domain (Pfc11_Clp1_ID)Pcf11, Clp1-interaction domainPcf11 is a subunit and an essential component of the cleavage and polyadenylation factor CFIA from yeast and the orthologue from human CFII which is involved in pre-mRNA 3' end processing and in transcription termination [1,3]. Pcf11-mediated termina ...Pcf11 is a subunit and an essential component of the cleavage and polyadenylation factor CFIA from yeast and the orthologue from human CFII which is involved in pre-mRNA 3' end processing and in transcription termination [1,3]. Pcf11-mediated termination is essential for vertebrate development [2]. Pcf11 binds to Clp1, another subunit of CFIA/CFII, whose interaction is responsible for maintaining a tight coupling between the Clp1 nucleotide binding subunit and the other components of the polyadenylation machinery [1-3]. This entry represents the Clp1-interaction region (Clp1 ID) of Pcf11 from yeast and vertebrates.
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
MRNA CLEAVAGE AND POLYADENYLATION FACTOR CLP1
C, D
PCF11P