Annotations: 4CD3

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d4cd3a2	Alpha and beta proteins (a/b)	Ribonuclease H-like motif	Actin-like ATPase domain	NTPDase (Nucleoside triphosphate diphosphohydrolase)-like	automated matches	NORWAY RAT (Rattus norvegicus ) [TaxId: 10116 ],	SCOPe (2.08)
A	d4cd3a1	Alpha and beta proteins (a/b)	Ribonuclease H-like motif	Actin-like ATPase domain	automated matches	automated matches	NORWAY RAT (Rattus norvegicus ) [TaxId: 10116 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	GDA1_CD39_C	e4cd3A5	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: GDA1_CD39_C	ECOD (1.6)
A	GDA1_CD39_N	e4cd3A6	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: GDA1_CD39_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.420.40	Alpha Beta	2-Layer Sandwich	Nucleotidyltransferase	domain 5	CATH (4.3.0)
A	3.30.420.150	Alpha Beta	2-Layer Sandwich	Nucleotidyltransferase	domain 5	CATH (4.3.0)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 2	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding pyrophosphatase activity nucleoside diphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity GDP phosphatase activity ADP phosphatase activity ribonucleoside triphosphate phosphatase activity UDP phosphatase activity ATP hydrolysis activity ATP-dependent activity identical protein binding protein binding	multicellular organismal process regulation of body fluid levels wound healing response to stimulus cell activation hemostasis biological regulation blood coagulation response to stress coagulation cellular process regulation of biological quality response to wounding platelet activation multicellular organismal process regulation of body fluid levels wound healing response to stimulus cell activation hemostasis biological regulation blood coagulation response to stress coagulation cellular process regulation of biological quality response to wounding platelet activation response to peptide cellular response to tumor necrosis factor response to chemical response to cytokine cellular response to cytokine stimulus response to tumor necrosis factor response to auditory stimulus response to mechanical stimulus response to abiotic stimulus response to external stimulus response to interleukin-6 cellular response to interleukin-6 nucleoside phosphate metabolic process catabolic process cellular metabolic process organophosphate catabolic process primary metabolic process nucleoside phosphate catabolic process nucleobase-containing compound catabolic process nucleobase-containing compound metabolic process nucleoside diphosphate metabolic process organophosphate metabolic process nucleobase-containing small molecule metabolic process phosphate-containing compound metabolic process nucleoside diphosphate catabolic process metabolic process small molecule metabolic process phosphorus metabolic process ribonucleoside diphosphate metabolic process ribonucleoside diphosphate catabolic process purine nucleoside diphosphate metabolic process purine nucleoside diphosphate catabolic process purine ribonucleoside diphosphate metabolic process purine ribonucleoside diphosphate catabolic process cellular response to stimulus regulation of biological process regulation of cellular process signaling G protein-coupled receptor signaling pathway signal transduction cell communication biological process involved in interspecies interaction between organisms response to lipid response to other organism cellular response to lipopolysaccharide response to oxygen-containing compound cellular response to molecule of bacterial origin response to lipopolysaccharide cellular response to oxygen-containing compound response to biotic stimulus cellular response to biotic stimulus cellular response to chemical stimulus response to bacterium cellular response to lipid response to external biotic stimulus response to molecule of bacterial origin response to interferon-alpha cellular response to interferon-alpha	basement membrane cell periphery extracellular matrix external encapsulating structure collagen-containing extracellular matrix cellular anatomical entity cell surface plasma membrane membrane cell body cell projection plasma membrane region cell projection membrane plasma membrane bounded cell projection

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR000407	Nucleoside phosphatase GDA1/CD39	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.