4FEG
High-resolution structure of pyruvate oxidase in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate carbanion-enamine, crystal A
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
| Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
|---|---|---|---|---|---|---|---|---|
| B | d4fegb2 | Alpha and beta proteins (a/b) | DHS-like NAD/FAD-binding domain | DHS-like NAD/FAD-binding domain | automated matches | automated matches | (Lactiplantibacillus plantarum JDM1 ) [TaxId: 644042 ], | SCOPe (2.08) |
| B | d4fegb1 | Alpha and beta proteins (a/b) | Thiamin diphosphate-binding fold (THDP-binding) | Thiamin diphosphate-binding fold (THDP-binding) | automated matches | automated matches | (Lactiplantibacillus plantarum JDM1 ) [TaxId: 644042 ], | SCOPe (2.08) |
| A | d4fega2 | Alpha and beta proteins (a/b) | DHS-like NAD/FAD-binding domain | DHS-like NAD/FAD-binding domain | automated matches | automated matches | (Lactiplantibacillus plantarum JDM1 ) [TaxId: 644042 ], | SCOPe (2.08) |
| A | d4fega1 | Alpha and beta proteins (a/b) | Thiamin diphosphate-binding fold (THDP-binding) | Thiamin diphosphate-binding fold (THDP-binding) | automated matches | automated matches | (Lactiplantibacillus plantarum JDM1 ) [TaxId: 644042 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
| Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
|---|---|---|---|---|---|---|---|---|
| B | TPP_enzyme_M | e4fegB6 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: DHS-like NAD/FAD-binding domain | F: TPP_enzyme_M | ECOD (1.6) |
| B | TPP_enzyme_C | e4fegB4 | A: a/b three-layered sandwiches | X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | T: Thiamin diphosphate-binding fold (THDP-binding) | F: TPP_enzyme_C | ECOD (1.6) |
| B | TPP_enzyme_N | e4fegB5 | A: a/b three-layered sandwiches | X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | T: Thiamin diphosphate-binding fold (THDP-binding) | F: TPP_enzyme_N | ECOD (1.6) |
| A | TPP_enzyme_M | e4fegA6 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: DHS-like NAD/FAD-binding domain | F: TPP_enzyme_M | ECOD (1.6) |
| A | TPP_enzyme_C | e4fegA4 | A: a/b three-layered sandwiches | X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | T: Thiamin diphosphate-binding fold (THDP-binding) | F: TPP_enzyme_C | ECOD (1.6) |
| A | TPP_enzyme_N | e4fegA5 | A: a/b three-layered sandwiches | X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | T: Thiamin diphosphate-binding fold (THDP-binding) | F: TPP_enzyme_N | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
| Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
|---|---|---|---|---|---|---|
| B | 3.40.50.970 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains | CATH (4.3.0) |
| B | 3.40.50.1220 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | TPP-binding domain | CATH (4.3.0) |
| A | 3.40.50.970 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains | CATH (4.3.0) |
| A | 3.40.50.1220 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | TPP-binding domain | CATH (4.3.0) |
