Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyTrimeric LpxA-like enzymes 8091508 3001804 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMurE/MurF N-terminal domain 8091500 3000146 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyMurE/MurF N-terminal domain 8091500 3000146 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyTrimeric LpxA-like enzymes 8091508 3001804 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyMurE/MurF N-terminal domain 8091500 3000146 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyTrimeric LpxA-like enzymes 8091508 3001804 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyTrimeric LpxA-like enzymes 8091508 3001804 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyMurE/MurF N-terminal domain 8091500 3000146 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyMurE/MurF N-terminal domain 8091500 3000146 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyTrimeric LpxA-like enzymes 8091508 3001804 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyTrimeric LpxA-like enzymes 8091508 3001804 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyMurE/MurF N-terminal domain 8091500 3000146 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AHexapep_2_1e4ihhA2 A: beta duplicates or obligate multimersX: Single-stranded left-handed beta-helixH: Trimeric LpxA-like enzymes (From Topology)T: Trimeric LpxA-like enzymesF: Hexapep_2_1ECOD (1.6)
AHexapepe4ihhA1 A: beta duplicates or obligate multimersX: Single-stranded left-handed beta-helixH: Trimeric LpxA-like enzymes (From Topology)T: Trimeric LpxA-like enzymesF: HexapepECOD (1.6)
ALpxDe4ihhA3 A: a/b three-layered sandwichesX: MurF and HprK N-domain-like (From Topology)H: MurF and HprK N-domain-like (From Topology)T: MurF and HprK N-domain-likeF: LpxDECOD (1.6)
BHexapep_2_1e4ihhB2 A: beta duplicates or obligate multimersX: Single-stranded left-handed beta-helixH: Trimeric LpxA-like enzymes (From Topology)T: Trimeric LpxA-like enzymesF: Hexapep_2_1ECOD (1.6)
BHexapepe4ihhB1 A: beta duplicates or obligate multimersX: Single-stranded left-handed beta-helixH: Trimeric LpxA-like enzymes (From Topology)T: Trimeric LpxA-like enzymesF: HexapepECOD (1.6)
BLpxDe4ihhB3 A: a/b three-layered sandwichesX: MurF and HprK N-domain-like (From Topology)H: MurF and HprK N-domain-like (From Topology)T: MurF and HprK N-domain-likeF: LpxDECOD (1.6)
CHexapep_2_1e4ihhC2 A: beta duplicates or obligate multimersX: Single-stranded left-handed beta-helixH: Trimeric LpxA-like enzymes (From Topology)T: Trimeric LpxA-like enzymesF: Hexapep_2_1ECOD (1.6)
CHexapepe4ihhC1 A: beta duplicates or obligate multimersX: Single-stranded left-handed beta-helixH: Trimeric LpxA-like enzymes (From Topology)T: Trimeric LpxA-like enzymesF: HexapepECOD (1.6)
CLpxDe4ihhC3 A: a/b three-layered sandwichesX: MurF and HprK N-domain-like (From Topology)H: MurF and HprK N-domain-like (From Topology)T: MurF and HprK N-domain-likeF: LpxDECOD (1.6)
DHexapep_2_1e4ihhD2 A: beta duplicates or obligate multimersX: Single-stranded left-handed beta-helixH: Trimeric LpxA-like enzymes (From Topology)T: Trimeric LpxA-like enzymesF: Hexapep_2_1ECOD (1.6)
DHexapepe4ihhD1 A: beta duplicates or obligate multimersX: Single-stranded left-handed beta-helixH: Trimeric LpxA-like enzymes (From Topology)T: Trimeric LpxA-like enzymesF: HexapepECOD (1.6)
DLpxDe4ihhD3 A: a/b three-layered sandwichesX: MurF and HprK N-domain-like (From Topology)H: MurF and HprK N-domain-like (From Topology)T: MurF and HprK N-domain-likeF: LpxDECOD (1.6)
EHexapep_2_1e4ihhE2 A: beta duplicates or obligate multimersX: Single-stranded left-handed beta-helixH: Trimeric LpxA-like enzymes (From Topology)T: Trimeric LpxA-like enzymesF: Hexapep_2_1ECOD (1.6)
EHexapepe4ihhE1 A: beta duplicates or obligate multimersX: Single-stranded left-handed beta-helixH: Trimeric LpxA-like enzymes (From Topology)T: Trimeric LpxA-like enzymesF: HexapepECOD (1.6)
ELpxDe4ihhE3 A: a/b three-layered sandwichesX: MurF and HprK N-domain-like (From Topology)H: MurF and HprK N-domain-like (From Topology)T: MurF and HprK N-domain-likeF: LpxDECOD (1.6)
FHexapep_2_1e4ihhF2 A: beta duplicates or obligate multimersX: Single-stranded left-handed beta-helixH: Trimeric LpxA-like enzymes (From Topology)T: Trimeric LpxA-like enzymesF: Hexapep_2_1ECOD (1.6)
FHexapepe4ihhF1 A: beta duplicates or obligate multimersX: Single-stranded left-handed beta-helixH: Trimeric LpxA-like enzymes (From Topology)T: Trimeric LpxA-like enzymesF: HexapepECOD (1.6)
FLpxDe4ihhF3 A: a/b three-layered sandwichesX: MurF and HprK N-domain-like (From Topology)H: MurF and HprK N-domain-like (From Topology)T: MurF and HprK N-domain-likeF: LpxDECOD (1.6)
IPP-bindinge4ihhI1 A: alpha bundlesX: ACP-likeH: Acyl-carrier protein (ACP) (From Topology)T: Acyl-carrier protein (ACP)F: PP-bindingECOD (1.6)
GPP-bindinge4ihhG1 A: alpha bundlesX: ACP-likeH: Acyl-carrier protein (ACP) (From Topology)T: Acyl-carrier protein (ACP)F: PP-bindingECOD (1.6)
JPP-bindinge4ihhJ1 A: alpha bundlesX: ACP-likeH: Acyl-carrier protein (ACP) (From Topology)T: Acyl-carrier protein (ACP)F: PP-bindingECOD (1.6)
KPP-bindinge4ihhK1 A: alpha bundlesX: ACP-likeH: Acyl-carrier protein (ACP) (From Topology)T: Acyl-carrier protein (ACP)F: PP-bindingECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.40.1390.10 Alpha Beta 3-Layer(aba) Sandwich Udp-n-acetylmuramoylalanyl-d-glutamate--2,6- Diaminopimelate Ligase Chain: A, domain 1CATH (4.3.0)
A2.160.10.10 Mainly Beta 3 Solenoid UDP N-Acetylglucosamine Acyltransferase domain 1CATH (4.3.0)
B3.40.1390.10 Alpha Beta 3-Layer(aba) Sandwich Udp-n-acetylmuramoylalanyl-d-glutamate--2,6- Diaminopimelate Ligase Chain: A, domain 1CATH (4.3.0)
B2.160.10.10 Mainly Beta 3 Solenoid UDP N-Acetylglucosamine Acyltransferase domain 1CATH (4.3.0)
C3.40.1390.10 Alpha Beta 3-Layer(aba) Sandwich Udp-n-acetylmuramoylalanyl-d-glutamate--2,6- Diaminopimelate Ligase Chain: A, domain 1CATH (4.3.0)
C2.160.10.10 Mainly Beta 3 Solenoid UDP N-Acetylglucosamine Acyltransferase domain 1CATH (4.3.0)
D3.40.1390.10 Alpha Beta 3-Layer(aba) Sandwich Udp-n-acetylmuramoylalanyl-d-glutamate--2,6- Diaminopimelate Ligase Chain: A, domain 1CATH (4.3.0)
D2.160.10.10 Mainly Beta 3 Solenoid UDP N-Acetylglucosamine Acyltransferase domain 1CATH (4.3.0)
E3.40.1390.10 Alpha Beta 3-Layer(aba) Sandwich Udp-n-acetylmuramoylalanyl-d-glutamate--2,6- Diaminopimelate Ligase Chain: A, domain 1CATH (4.3.0)
E2.160.10.10 Mainly Beta 3 Solenoid UDP N-Acetylglucosamine Acyltransferase domain 1CATH (4.3.0)
F3.40.1390.10 Alpha Beta 3-Layer(aba) Sandwich Udp-n-acetylmuramoylalanyl-d-glutamate--2,6- Diaminopimelate Ligase Chain: A, domain 1CATH (4.3.0)
F2.160.10.10 Mainly Beta 3 Solenoid UDP N-Acetylglucosamine Acyltransferase domain 1CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D, E
PF00132Bacterial transferase hexapeptide (six repeats) (Hexapep)Bacterial transferase hexapeptide (six repeats)- Repeat
A, B, C, D, E
PF04613UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD (LpxD)UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxDUDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase (EC 2.3.1.-) catalyses an early step in lipid A biosynthesis: UDP-3-O-(3-hydroxytetradecanoyl)glucosamine + (R)-3-hydroxytetradecanoyl- [acyl carrier protein] -> UDP-2,3-bis(3-hydroxytetradec ...UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase (EC 2.3.1.-) catalyses an early step in lipid A biosynthesis: UDP-3-O-(3-hydroxytetradecanoyl)glucosamine + (R)-3-hydroxytetradecanoyl- [acyl carrier protein] -> UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + [acyl carrier protein] [1]. Members of this family also contain a hexapeptide repeat (Pfam:PF00132). This family constitutes the non-repeating region of LPXD proteins.
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D, E
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase
G, H, I, J, K
Acyl carrier protein---

InterPro: Protein Family Classification InterPro Database Homepage