4POP

ThiT with LMG139 bound

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: PDBTM
Membrane Protein Annotation: MemProtMD

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	ThiA-like	8045013	4004255	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Gx transporter-like	8054029	3002268	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	Gx transporter-like	8054029	3002268	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Thia_YuaJ	e4popA1	A: alpha bundles	X: Spectrin repeat-like	H: MIT domain (From Topology)	T: MIT domain	F: Thia_YuaJ	ECOD (1.6)
B	Thia_YuaJ	e4popB1	A: alpha bundles	X: Spectrin repeat-like	H: MIT domain (From Topology)	T: MIT domain	F: Thia_YuaJ	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.1760.20	Mainly Alpha	Orthogonal Bundle	Arp2/3 complex 21 kDa subunit ARPC3		CATH (4.3.0)
B	1.10.1760.20	Mainly Alpha	Orthogonal Bundle	Arp2/3 complex 21 kDa subunit ARPC3		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF09515	Thiamine transporter protein (Thia_YuaJ) (Thia_YuaJ)	Thiamine transporter protein (Thia_YuaJ)	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Thiamine transporter ThiT	thiamine transmembrane transporter activity organic cation transmembrane transporter activity azole transmembrane transporter activity sulfur compound transmembrane transporter activity vitamin transmembrane transporter activity transporter activity transmembrane transporter activity	-	cell periphery cellular anatomical structure plasma membrane membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR012651	Thiamine transporter ThiT	Family

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A, B	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A, B	MemProtMD	Annotated as membrane protein by MemProtMD

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.