4WH0

YcaC from Pseudomonas aeruginosa with S-mercaptocysteine active site cysteine

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Protein Modification Annotation

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d4wh0a_	Alpha and beta proteins (a/b)	Isochorismatase-like hydrolases	Isochorismatase-like hydrolases	Isochorismatase-like hydrolases	automated matches	(Pseudomonas aeruginosa ) [TaxId: 287 ],	SCOPe (2.08)
B	d4wh0b_	Alpha and beta proteins (a/b)	Isochorismatase-like hydrolases	Isochorismatase-like hydrolases	Isochorismatase-like hydrolases	automated matches	(Pseudomonas aeruginosa ) [TaxId: 287 ],	SCOPe (2.08)
C	d4wh0c_	Alpha and beta proteins (a/b)	Isochorismatase-like hydrolases	Isochorismatase-like hydrolases	Isochorismatase-like hydrolases	automated matches	(Pseudomonas aeruginosa ) [TaxId: 287 ],	SCOPe (2.08)
D	d4wh0d_	Alpha and beta proteins (a/b)	Isochorismatase-like hydrolases	Isochorismatase-like hydrolases	Isochorismatase-like hydrolases	automated matches	(Pseudomonas aeruginosa ) [TaxId: 287 ],	SCOPe (2.08)
E	d4wh0e_	Alpha and beta proteins (a/b)	Isochorismatase-like hydrolases	Isochorismatase-like hydrolases	Isochorismatase-like hydrolases	automated matches	(Pseudomonas aeruginosa ) [TaxId: 287 ],	SCOPe (2.08)
F	d4wh0f_	Alpha and beta proteins (a/b)	Isochorismatase-like hydrolases	Isochorismatase-like hydrolases	Isochorismatase-like hydrolases	automated matches	(Pseudomonas aeruginosa ) [TaxId: 287 ],	SCOPe (2.08)
G	d4wh0g_	Alpha and beta proteins (a/b)	Isochorismatase-like hydrolases	Isochorismatase-like hydrolases	Isochorismatase-like hydrolases	automated matches	(Pseudomonas aeruginosa ) [TaxId: 287 ],	SCOPe (2.08)
H	d4wh0h_	Alpha and beta proteins (a/b)	Isochorismatase-like hydrolases	Isochorismatase-like hydrolases	Isochorismatase-like hydrolases	automated matches	(Pseudomonas aeruginosa ) [TaxId: 287 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Isochorismatase-like hydrolases	8078463	3001778	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Isochorismatase-like hydrolases	8078463	3001778	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Isochorismatase-like hydrolases	8078463	3001778	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Isochorismatase-like hydrolases	8078463	3001778	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Isochorismatase-like hydrolases	8078463	3001778	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Isochorismatase-like hydrolases	8078463	3001778	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Isochorismatase-like hydrolases	8078463	3001778	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Isochorismatase-like hydrolases	8078463	3001778	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Isochorismatase	e4wh0A1	A: a/b three-layered sandwiches	X: Isochorismatase-like hydrolases (From Topology)	H: Isochorismatase-like hydrolases (From Topology)	T: Isochorismatase-like hydrolases	F: Isochorismatase	ECOD (1.6)
B	Isochorismatase	e4wh0B1	A: a/b three-layered sandwiches	X: Isochorismatase-like hydrolases (From Topology)	H: Isochorismatase-like hydrolases (From Topology)	T: Isochorismatase-like hydrolases	F: Isochorismatase	ECOD (1.6)
C	Isochorismatase	e4wh0C1	A: a/b three-layered sandwiches	X: Isochorismatase-like hydrolases (From Topology)	H: Isochorismatase-like hydrolases (From Topology)	T: Isochorismatase-like hydrolases	F: Isochorismatase	ECOD (1.6)
D	Isochorismatase	e4wh0D1	A: a/b three-layered sandwiches	X: Isochorismatase-like hydrolases (From Topology)	H: Isochorismatase-like hydrolases (From Topology)	T: Isochorismatase-like hydrolases	F: Isochorismatase	ECOD (1.6)
E	Isochorismatase	e4wh0E1	A: a/b three-layered sandwiches	X: Isochorismatase-like hydrolases (From Topology)	H: Isochorismatase-like hydrolases (From Topology)	T: Isochorismatase-like hydrolases	F: Isochorismatase	ECOD (1.6)
F	Isochorismatase	e4wh0F1	A: a/b three-layered sandwiches	X: Isochorismatase-like hydrolases (From Topology)	H: Isochorismatase-like hydrolases (From Topology)	T: Isochorismatase-like hydrolases	F: Isochorismatase	ECOD (1.6)
G	Isochorismatase	e4wh0G1	A: a/b three-layered sandwiches	X: Isochorismatase-like hydrolases (From Topology)	H: Isochorismatase-like hydrolases (From Topology)	T: Isochorismatase-like hydrolases	F: Isochorismatase	ECOD (1.6)
H	Isochorismatase	e4wh0H1	A: a/b three-layered sandwiches	X: Isochorismatase-like hydrolases (From Topology)	H: Isochorismatase-like hydrolases (From Topology)	T: Isochorismatase-like hydrolases	F: Isochorismatase	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.850	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Isochorismatase-like	CATH (4.3.0)
B	3.40.50.850	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Isochorismatase-like	CATH (4.3.0)
C	3.40.50.850	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Isochorismatase-like	CATH (4.3.0)
D	3.40.50.850	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Isochorismatase-like	CATH (4.3.0)
E	3.40.50.850	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Isochorismatase-like	CATH (4.3.0)
F	3.40.50.850	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Isochorismatase-like	CATH (4.3.0)
G	3.40.50.850	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Isochorismatase-like	CATH (4.3.0)
H	3.40.50.850	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Isochorismatase-like	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H	PF00857	Isochorismatase family (Isochorismatase)	Isochorismatase family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H	Putative hydrolase	hydrolase activity catalytic activity	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H	IPR000868	Isochorismatase-like	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	IPR048239	Probable hydrolase YcaC	Family
A, B, C, D, E A, B, C, D, E, F, G, H	IPR053152	Probable Hydrolase YcaC-like	Family
A, B, C, D, E A, B, C, D, E, F, G, H	IPR036380	Isochorismatase-like superfamily	Homologous Superfamily

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
A, B, C, D, E A, B, C, D, E, F, G, H	CSS	Parent Component: CYS RESID: AA0269 PSI-MOD : L-cysteine persulfide MOD:00274
A, B, C, D, E A, B, C, D, E, F, G, H	MSE	Parent Component: MET RESID: AA0269

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.