4WX8

Crystal structure of binary complex Gon7-Pcc1

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Pcc1-like	8052135	3002095	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Pcc1-like	8052135	3002095	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Pcc1-like	8052135	3002095	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Pcc1	e4wx8A1	A: a+b two layers	X: protein PCC1 (From Topology)	H: protein PCC1 (From Topology)	T: protein PCC1	F: Pcc1	ECOD (1.6)
B	Pcc1	e4wx8B1	A: a+b two layers	X: protein PCC1 (From Topology)	H: protein PCC1 (From Topology)	T: protein PCC1	F: Pcc1	ECOD (1.6)
C	Pcc1	e4wx8C1	A: a+b two layers	X: protein PCC1 (From Topology)	H: protein PCC1 (From Topology)	T: protein PCC1	F: Pcc1	ECOD (1.6)
D	Gon7	e4wx8D1	A: a+b two layers	X: EKC/KEOPS complex subunit GON7 (From Topology)	H: EKC/KEOPS complex subunit GON7 (From Topology)	T: EKC/KEOPS complex subunit GON7	F: Gon7	ECOD (1.6)
E	Gon7	e4wx8E1	A: a+b two layers	X: EKC/KEOPS complex subunit GON7 (From Topology)	H: EKC/KEOPS complex subunit GON7 (From Topology)	T: EKC/KEOPS complex subunit GON7	F: Gon7	ECOD (1.6)
F	Gon7	e4wx8F1	A: a+b two layers	X: EKC/KEOPS complex subunit GON7 (From Topology)	H: EKC/KEOPS complex subunit GON7 (From Topology)	T: EKC/KEOPS complex subunit GON7	F: Gon7	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.310.50	Alpha Beta	2-Layer Sandwich	TATA-Binding Protein	Alpha-D-phosphohexomutase, C-terminal domain	CATH (4.3.0)
B	3.30.310.50	Alpha Beta	2-Layer Sandwich	TATA-Binding Protein	Alpha-D-phosphohexomutase, C-terminal domain	CATH (4.3.0)
C	3.30.310.50	Alpha Beta	2-Layer Sandwich	TATA-Binding Protein	Alpha-D-phosphohexomutase, C-terminal domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF09341	Transcription factor Pcc1 (Pcc1)	Transcription factor Pcc1	-	Family
D, E, F	PF08738	Gon7 family (Gon7)	Gon7 family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	EKC/KEOPS complex subunit PCC1	DNA binding binding chromatin binding organic cyclic compound binding nucleic acid binding chromatin DNA binding	tRNA threonylcarbamoyladenosine modification cellular biosynthetic process RNA metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process tRNA processing tRNA threonylcarbamoyladenosine metabolic process RNA processing cellular metabolic process tRNA modification primary metabolic process gene expression nucleobase-containing compound biosynthetic process tRNA threonylcarbamoyladenosine modification cellular biosynthetic process RNA metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process tRNA processing tRNA threonylcarbamoyladenosine metabolic process RNA processing cellular metabolic process tRNA modification primary metabolic process gene expression nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid metabolic process tRNA metabolic process RNA modification biosynthetic process macromolecule modification metabolic process cellular process macromolecule metabolic process cellular response to stimulus cellular response to chemical stimulus response to stimulus response to chemical response to pheromone cellular response to pheromone DNA recombination mitotic recombination telomere organization chromosome organization DNA metabolic process telomere maintenance cellular component organization organelle organization telomere maintenance via recombination cellular component organization or biogenesis maintenance of translational fidelity translation protein metabolic process regulation of cellular process positive regulation of DNA-templated transcription positive regulation of biological process positive regulation of cellular metabolic process positive regulation of macromolecule biosynthetic process regulation of primary metabolic process positive regulation of metabolic process DNA-templated transcription regulation of RNA metabolic process transcription by RNA polymerase II positive regulation of biosynthetic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process positive regulation of cellular process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of transcription by RNA polymerase II regulation of biological process positive regulation of nucleobase-containing compound metabolic process biological regulation regulation of cellular metabolic process regulation of macromolecule metabolic process positive regulation of transcription by RNA polymerase II regulation of cellular biosynthetic process positive regulation of RNA metabolic process regulation of gene expression positive regulation of RNA biosynthetic process regulation of macromolecule biosynthetic process regulation of DNA-templated transcription regulation of metabolic process positive regulation of cellular biosynthetic process	protein-containing complex catalytic complex transferase complex EKC/KEOPS complex intracellular organelle intracellular anatomical structure organelle intracellular non-membrane-bounded organelle chromosome chromosome, telomeric region cellular anatomical entity chromosomal region non-membrane-bounded organelle membrane-bounded organelle protein-containing complex catalytic complex transferase complex EKC/KEOPS complex intracellular organelle intracellular anatomical structure organelle intracellular non-membrane-bounded organelle chromosome chromosome, telomeric region cellular anatomical entity chromosomal region non-membrane-bounded organelle membrane-bounded organelle nucleus membrane-enclosed lumen intracellular membrane-bounded organelle intracellular organelle lumen nucleoplasm organelle lumen nuclear lumen chromatin
D, E, F	EKC/KEOPS complex subunit GON7	DNA binding binding chromatin binding organic cyclic compound binding nucleic acid binding chromatin DNA binding molecular adaptor activity	tRNA threonylcarbamoyladenosine modification cellular biosynthetic process RNA metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process tRNA processing tRNA threonylcarbamoyladenosine metabolic process RNA processing cellular metabolic process tRNA modification primary metabolic process gene expression nucleobase-containing compound biosynthetic process tRNA threonylcarbamoyladenosine modification cellular biosynthetic process RNA metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process tRNA processing tRNA threonylcarbamoyladenosine metabolic process RNA processing cellular metabolic process tRNA modification primary metabolic process gene expression nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid metabolic process tRNA metabolic process RNA modification biosynthetic process macromolecule modification metabolic process cellular process macromolecule metabolic process DNA recombination mitotic recombination telomere organization chromosome organization DNA metabolic process telomere maintenance cellular component organization organelle organization telomere maintenance via recombination cellular component organization or biogenesis carbohydrate derivative biosynthetic process mannoprotein biosynthetic process cell wall mannoprotein biosynthetic process cell wall organization or biogenesis glycoprotein biosynthetic process carbohydrate derivative metabolic process glycoprotein metabolic process mannoprotein metabolic process protein metabolic process cell wall glycoprotein biosynthetic process cell wall macromolecule metabolic process maintenance of translational fidelity translation regulation of cellular process positive regulation of DNA-templated transcription positive regulation of biological process positive regulation of cellular metabolic process positive regulation of macromolecule biosynthetic process regulation of primary metabolic process positive regulation of metabolic process DNA-templated transcription regulation of RNA metabolic process transcription by RNA polymerase II positive regulation of biosynthetic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process positive regulation of cellular process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of transcription by RNA polymerase II regulation of biological process positive regulation of nucleobase-containing compound metabolic process biological regulation regulation of cellular metabolic process regulation of macromolecule metabolic process positive regulation of transcription by RNA polymerase II regulation of cellular biosynthetic process positive regulation of RNA metabolic process regulation of gene expression positive regulation of RNA biosynthetic process regulation of macromolecule biosynthetic process regulation of DNA-templated transcription regulation of metabolic process positive regulation of cellular biosynthetic process	protein-containing complex catalytic complex transferase complex EKC/KEOPS complex intracellular organelle intracellular anatomical structure organelle intracellular non-membrane-bounded organelle chromosome chromosome, telomeric region cellular anatomical entity chromosomal region non-membrane-bounded organelle chromatin protein-containing complex catalytic complex transferase complex EKC/KEOPS complex intracellular organelle intracellular anatomical structure organelle intracellular non-membrane-bounded organelle chromosome chromosome, telomeric region cellular anatomical entity chromosomal region non-membrane-bounded organelle chromatin membrane-bounded organelle nucleus intracellular membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR015419	CTAG/Pcc1 family	Family
D, E, F	IPR014849	EKC/KEOPS complex, subunit Gon7	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.