Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ADNA_pol_A_2nde4yfuA1 A: alpha arraysX: helical bundle in Bacillus stearothermophilus-like DNA polymerase I (From Topology)H: helical bundle in Bacillus stearothermophilus-like DNA polymerase I (From Topology)T: helical bundle in Bacillus stearothermophilus-like DNA polymerase IF: DNA_pol_A_2ndECOD (1.6)
ADNA_pol_A_1ste4yfuA2 A: alpha bundlesX: fingers domain in bacteriophage RB69-like DNA polymerase I (From Topology)H: fingers domain in bacteriophage RB69-like DNA polymerase I (From Topology)T: fingers domain in bacteriophage RB69-like DNA polymerase IF: DNA_pol_A_1stECOD (1.6)
ADNA_pol_A_3rde4yfuA3 A: a+b two layersX: Alpha-beta plaitsH: Adenylyl and guanylyl cyclase catalytic domain-likeT: Adenylyl and guanylyl cyclase catalytic domain-likeF: DNA_pol_A_3rdECOD (1.6)
ADNA_pol_A_exo1_1e4yfuA4 A: mixed a+b and a/bX: Ribonuclease H-likeH: Ribonuclease H-like (From Topology)T: Ribonuclease H-likeF: DNA_pol_A_exo1_1ECOD (1.6)
B [auth D]DNA_pol_A_2nde4yfuD4 A: alpha arraysX: helical bundle in Bacillus stearothermophilus-like DNA polymerase I (From Topology)H: helical bundle in Bacillus stearothermophilus-like DNA polymerase I (From Topology)T: helical bundle in Bacillus stearothermophilus-like DNA polymerase IF: DNA_pol_A_2ndECOD (1.6)
B [auth D]DNA_pol_A_1ste4yfuD1 A: alpha bundlesX: fingers domain in bacteriophage RB69-like DNA polymerase I (From Topology)H: fingers domain in bacteriophage RB69-like DNA polymerase I (From Topology)T: fingers domain in bacteriophage RB69-like DNA polymerase IF: DNA_pol_A_1stECOD (1.6)
B [auth D]DNA_pol_A_3rde4yfuD2 A: a+b two layersX: Alpha-beta plaitsH: Adenylyl and guanylyl cyclase catalytic domain-likeT: Adenylyl and guanylyl cyclase catalytic domain-likeF: DNA_pol_A_3rdECOD (1.6)
B [auth D]DNA_pol_A_exo1_1e4yfuD3 A: mixed a+b and a/bX: Ribonuclease H-likeH: Ribonuclease H-like (From Topology)T: Ribonuclease H-likeF: DNA_pol_A_exo1_1ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.30.420.10 Alpha Beta 2-Layer Sandwich Nucleotidyltransferase domain 5CATH (4.3.0)
A1.20.1060.10 Mainly Alpha Up-down Bundle Taq DNA Polymerase Chain T, domain 4CATH (4.3.0)
A3.30.70.370 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits CATH (4.3.0)
B [auth D]3.30.420.10 Alpha Beta 2-Layer Sandwich Nucleotidyltransferase domain 5CATH (4.3.0)
B [auth D]1.20.1060.10 Mainly Alpha Up-down Bundle Taq DNA Polymerase Chain T, domain 4CATH (4.3.0)
B [auth D]3.30.70.370 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A,
B [auth D]
PF22619DNA polymerase I, ribonuclease H-like domain (DNA_polI_exo1)DNA polymerase I, ribonuclease H-like domainThis domain is responsible for the 3'-5' exonuclease proofreading activity of E. coli DNA polymerase I (polI) and other related enzymes. It is one of the constituent domains of Klenow fragment.Domain
A,
B [auth D]
PF00476DNA polymerase family A (DNA_pol_A)DNA polymerase family A- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A,
B [auth D]
DNA polymerase -
C [auth B],
E
Primer DNA---
D [auth C],
F
Template DNA---