4ZU7

X-ray structure if the QdtA 3,4-ketoisomerase from Thermoanaerobacterium thermosaccharolyticum, double mutant Y17R/R97H, in complex with TDP

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d4zu7a1	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	(Thermoanaerobacterium thermosaccharolyticum ) [TaxId: 1517 ],	SCOPe (2.08)
A	d4zu7a2	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Thermoanaerobacterium thermosaccharolyticum ) [TaxId: 1517 ],	SCOPe (2.08)
B	d4zu7b1	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	(Thermoanaerobacterium thermosaccharolyticum ) [TaxId: 1517 ],	SCOPe (2.08)
B	d4zu7b2	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Thermoanaerobacterium thermosaccharolyticum ) [TaxId: 1517 ],	SCOPe (2.08)
G	d4zu7g_	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	(Thermoanaerobacterium thermosaccharolyticum ) [TaxId: 1517 ],	SCOPe (2.08)
H	d4zu7h_	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	(Thermoanaerobacterium thermosaccharolyticum ) [TaxId: 1517 ],	SCOPe (2.08)
C	d4zu7c1	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	(Thermoanaerobacterium thermosaccharolyticum ) [TaxId: 1517 ],	SCOPe (2.08)
C	d4zu7c2	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Thermoanaerobacterium thermosaccharolyticum ) [TaxId: 1517 ],	SCOPe (2.08)
D	d4zu7d1	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	(Thermoanaerobacterium thermosaccharolyticum ) [TaxId: 1517 ],	SCOPe (2.08)
D	d4zu7d2	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Thermoanaerobacterium thermosaccharolyticum ) [TaxId: 1517 ],	SCOPe (2.08)
E	d4zu7e1	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	(Thermoanaerobacterium thermosaccharolyticum ) [TaxId: 1517 ],	SCOPe (2.08)
E	d4zu7e2	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Thermoanaerobacterium thermosaccharolyticum ) [TaxId: 1517 ],	SCOPe (2.08)
F	d4zu7f1	All beta proteins	Double-stranded beta-helix	RmlC-like cupins	automated matches	automated matches	(Thermoanaerobacterium thermosaccharolyticum ) [TaxId: 1517 ],	SCOPe (2.08)
F	d4zu7f2	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Thermoanaerobacterium thermosaccharolyticum ) [TaxId: 1517 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	RmlC-like cupins	8086548	3001825	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	RmlC-like cupins	8086548	3001825	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	RmlC-like cupins	8086548	3001825	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	RmlC-like cupins	8086548	3001825	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	RmlC-like cupins	8086548	3001825	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	RmlC-like cupins	8086548	3001825	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	RmlC-like cupins	8086548	3001825	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	RmlC-like cupins	8086548	3001825	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	FdtA	e4zu7A1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: FdtA	ECOD (1.6)
B	FdtA	e4zu7B1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: FdtA	ECOD (1.6)
G	FdtA	e4zu7G1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: FdtA	ECOD (1.6)
H	FdtA	e4zu7H1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: FdtA	ECOD (1.6)
C	FdtA	e4zu7C1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: FdtA	ECOD (1.6)
D	FdtA	e4zu7D1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: FdtA	ECOD (1.6)
E	FdtA	e4zu7E1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: FdtA	ECOD (1.6)
F	FdtA	e4zu7F1	A: beta sandwiches	X: jelly-roll	H: Double-stranded beta-helix (From Topology)	T: Double-stranded beta-helix	F: FdtA	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)
B	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)
G	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)
H	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)
C	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)
D	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)
E	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)
F	2.60.120.10	Mainly Beta	Sandwich	Jelly Rolls	Jelly Rolls	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H	PF05523	WxcM-like, C-terminal (FdtA)	WxcM-like, C-terminal	This family includes FdtA (Swiss:Q6T1W8) from Aneurinibacillus thermoaerophilus, which has been characterised as a dtdp-6-deoxy-3,4-keto-hexulose isomerase [1]. It also includes WxcM (Swiss:Q93S92) from Xanthomonas campestris (pv. campestris) [2].	Domain

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H	IPR008894	Sugar 3,4-ketoisomerase QdtA, cupin domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	IPR011051	RmlC-like cupin domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H	IPR014710	RmlC-like jelly roll fold	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.