4EIS

Structural basis for substrate targeting and catalysis by fungal polysaccharide monooxygenases (PMO-3)

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Protein Modification Annotation

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Glyco_hydro_61	e4eisA1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: Glyco_hydro_61	ECOD (1.6)
B	Glyco_hydro_61	e4eisB1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: Glyco_hydro_61	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.70.50.70	Mainly Beta	Distorted Sandwich	Coagulation Factor XIII	Chain A, domain 1	CATH (4.3.0)
B	2.70.50.70	Mainly Beta	Distorted Sandwich	Coagulation Factor XIII	Chain A, domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF03443	Auxiliary Activity family 9 (formerly GH61) (AA9)	Auxiliary Activity family 9 (formerly GH61)	-	Family
B	PF03443	Auxiliary Activity family 9 (formerly GH61) (AA9)	Auxiliary Activity family 9 (formerly GH61)	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	polysaccharide monooxygenase-3	cation binding ion binding binding metal ion binding small molecule binding	carbohydrate metabolic process catabolic process glucan catabolic process beta-glucan metabolic process carbohydrate catabolic process primary metabolic process macromolecule catabolic process polysaccharide metabolic process glucan metabolic process beta-glucan catabolic process polysaccharide catabolic process metabolic process cellulose catabolic process macromolecule metabolic process carbohydrate metabolic process catabolic process glucan catabolic process beta-glucan metabolic process carbohydrate catabolic process primary metabolic process macromolecule catabolic process polysaccharide metabolic process glucan metabolic process beta-glucan catabolic process polysaccharide catabolic process metabolic process cellulose catabolic process macromolecule metabolic process cellulose metabolic process	extracellular region cellular anatomical entity
B	polysaccharide monooxygenase-3	cation binding ion binding binding metal ion binding small molecule binding	carbohydrate metabolic process catabolic process glucan catabolic process beta-glucan metabolic process carbohydrate catabolic process primary metabolic process macromolecule catabolic process polysaccharide metabolic process glucan metabolic process beta-glucan catabolic process polysaccharide catabolic process metabolic process cellulose catabolic process macromolecule metabolic process carbohydrate metabolic process catabolic process glucan catabolic process beta-glucan metabolic process carbohydrate catabolic process primary metabolic process macromolecule catabolic process polysaccharide metabolic process glucan metabolic process beta-glucan catabolic process polysaccharide catabolic process metabolic process cellulose catabolic process macromolecule metabolic process cellulose metabolic process	extracellular region cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR049892	Auxiliary Activity family 9	Family
A	IPR005103	Auxiliary Activity family 9, catalytic domain	Domain
B	IPR049892	Auxiliary Activity family 9	Family
B	IPR005103	Auxiliary Activity family 9, catalytic domain	Domain

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
A	DAH	Parent Component: PHE RESID: AA0146 PSI-MOD : 3'-hydroxylation of L-tyrosine to L-3',4'-dihydroxyphenylalanine MOD:00155
A	HIC	Parent Component: HIS RESID: AA0146 , AA0317 PSI-MOD : 3'-hydroxylation of L-tyrosine to L-3',4'-dihydroxyphenylalanine MOD:00155 , 1'-methyl-L-histidine MOD:00322
B	HIC	Parent Component: HIS RESID: AA0146 , AA0317 , AA0317 PSI-MOD : 3'-hydroxylation of L-tyrosine to L-3',4'-dihydroxyphenylalanine MOD:00155 , 1'-methyl-L-histidine MOD:00322 , 1'-methyl-L-histidine MOD:00322

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.