Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AHexose_dehydrate4j7gA1 A: a+b two layersX: beta-GraspH: Nudix (From Topology)T: NudixF: Hexose_dehydratECOD (1.6)
BHexose_dehydrate4j7gB1 A: a+b two layersX: beta-GraspH: Nudix (From Topology)T: NudixF: Hexose_dehydratECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF03559NDP-hexose 2,3-dehydratase (Hexose_dehydrat)NDP-hexose 2,3-dehydrataseThis family includes a range of proteins from antibiotic production pathways. The family includes gra-ORF27 Swiss:Q9ZA32 product that probably functions at an early step, most likely as a dTDP-4-keto-6- deoxyglucose-2,3-dehydratase [1]. Its homologue ...This family includes a range of proteins from antibiotic production pathways. The family includes gra-ORF27 Swiss:Q9ZA32 product that probably functions at an early step, most likely as a dTDP-4-keto-6- deoxyglucose-2,3-dehydratase [1]. Its homologues include dnmT from the daunorubicin biosynthetic gene cluster in S. peucetius [2], a similar gene from the daunomycin biosynthetic cluster in Streptomyces sp. strain C5 Swiss:Q53880 [3] , eryBVI from the erythromycin cluster in S. erythraea and snoH from the nogalamycin cluster in S. nogalater. The proteins in this family are composed of two copies of a 200 amino acid long unit that may be a structural domain.
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
EvaA 2,3-dehydratase -