Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
A [auth E]SCOP2B SuperfamilyThioredoxin reductase-like 8056199 3000050 SCOP2B (2022-06-29)
A [auth E]SCOP2B SuperfamilyGSR C-terminal domain-like 8056200 3000028 SCOP2B (2022-06-29)
B [auth F]SCOP2B SuperfamilyGSR C-terminal domain-like 8056200 3000028 SCOP2B (2022-06-29)
B [auth F]SCOP2B SuperfamilyThioredoxin reductase-like 8056199 3000050 SCOP2B (2022-06-29)
C [auth A]SCOP2B SuperfamilyThioredoxin reductase-like 8056199 3000050 SCOP2B (2022-06-29)
C [auth A]SCOP2B SuperfamilyGSR C-terminal domain-like 8056200 3000028 SCOP2B (2022-06-29)
D [auth B]SCOP2B SuperfamilyThioredoxin reductase-like 8056199 3000050 SCOP2B (2022-06-29)
D [auth B]SCOP2B SuperfamilyGSR C-terminal domain-like 8056200 3000028 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
A [auth E]Pyr_redox_dime4kprE3 A: a+b two layersX: FAD-linked reductases, C-terminal domain-likeH: FAD/NAD-linked reduatases, dimerisation (C-terminal) domain (From Topology)T: FAD/NAD-linked reduatases, dimerisation (C-terminal) domainF: Pyr_redox_dimECOD (1.6)
A [auth E]Pyr_redox_2_1e4kprE1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2_1ECOD (1.6)
A [auth E]Pyr_redox_2e4kprE2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2ECOD (1.6)
B [auth F]Pyr_redox_dime4kprF3 A: a+b two layersX: FAD-linked reductases, C-terminal domain-likeH: FAD/NAD-linked reduatases, dimerisation (C-terminal) domain (From Topology)T: FAD/NAD-linked reduatases, dimerisation (C-terminal) domainF: Pyr_redox_dimECOD (1.6)
B [auth F]Pyr_redox_2_1e4kprF1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2_1ECOD (1.6)
B [auth F]Pyr_redox_2e4kprF2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2ECOD (1.6)
C [auth A]Pyr_redox_dime4kprA3 A: a+b two layersX: FAD-linked reductases, C-terminal domain-likeH: FAD/NAD-linked reduatases, dimerisation (C-terminal) domain (From Topology)T: FAD/NAD-linked reduatases, dimerisation (C-terminal) domainF: Pyr_redox_dimECOD (1.6)
C [auth A]Pyr_redox_2_1e4kprA1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2_1ECOD (1.6)
C [auth A]Pyr_redox_2e4kprA2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2ECOD (1.6)
D [auth B]Pyr_redox_dime4kprB3 A: a+b two layersX: FAD-linked reductases, C-terminal domain-likeH: FAD/NAD-linked reduatases, dimerisation (C-terminal) domain (From Topology)T: FAD/NAD-linked reduatases, dimerisation (C-terminal) domainF: Pyr_redox_dimECOD (1.6)
D [auth B]Pyr_redox_2_1e4kprB1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2_1ECOD (1.6)
D [auth B]Pyr_redox_2e4kprB2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A [auth E],
B [auth F],
C [auth A],
D [auth B]
PF00070Pyridine nucleotide-disulphide oxidoreductase (Pyr_redox)Pyridine nucleotide-disulphide oxidoreductaseThis family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.Domain
A [auth E],
B [auth F],
C [auth A],
D [auth B]
PF00890FAD binding domain (FAD_binding_2)FAD binding domain- Family
A [auth E],
B [auth F],
C [auth A],
D [auth B]
PF02852Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain (Pyr_redox_dim)Pyridine nucleotide-disulphide oxidoreductase, dimerisation domainThis family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A [auth E],
B [auth F],
C [auth A],
D [auth B]
Thioredoxin reductase 1, cytoplasmic