Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyNucleotidyltransferase-like 8042123 3000129 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyDNA polymerase beta, N-terminal domain-like 8037165 3000524 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyPsbU/PolX domain-like 8042122 3000893 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ADNA_pol_lambd_fe4qzbA2 A: alpha arraysX: HhH/H2THH: SAM/DNA-glycosylaseT: SAM domain-likeF: DNA_pol_lambd_fECOD (1.6)
AHHH_8e4qzbA3 A: alpha arraysX: HhH/H2THH: SAM/DNA-glycosylaseT: SAM domain-likeF: HHH_8ECOD (1.6)
ADNA_pol_B_palme4qzbA1 A: a+b three layersX: Nucleotidyltransferase-likeH: Nucleotidyltransferase (From Topology)T: NucleotidyltransferaseF: DNA_pol_B_palmECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A1.10.150.110 Mainly Alpha Orthogonal Bundle DNA polymerase domain 1CATH (4.3.0)
A1.10.150.20 Mainly Alpha Orthogonal Bundle DNA polymerase domain 1CATH (4.3.0)
A3.30.460.10 Alpha Beta 2-Layer Sandwich Beta Polymerase domain 2CATH (4.3.0)
A3.30.210.10 Alpha Beta 2-Layer Sandwich Beta Polymerase domain 3CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF14716Helix-hairpin-helix domain (HHH_8)Helix-hairpin-helix domain- Domain
PF14791DNA polymerase beta thumb (DNA_pol_B_thumb)DNA polymerase beta thumb- Family
PF10391Fingers domain of DNA polymerase lambda (DNA_pol_lambd_f)Fingers domain of DNA polymerase lambdaDNA polymerases catalyse the addition of dNMPs onto the 3-prime ends of DNA chains. There is a general polymerase fold consisting of three subdomains that have been likened to the fingers, palm, and thumb of a right hand. DNA_pol_lambd_f is the centr ...DNA polymerases catalyse the addition of dNMPs onto the 3-prime ends of DNA chains. There is a general polymerase fold consisting of three subdomains that have been likened to the fingers, palm, and thumb of a right hand. DNA_pol_lambd_f is the central three-helical region of DNA polymerase lambda referred to as the F and G helices of the fingers domain. Contacts with DNA involve this conserved helix-hairpin-helix motif in the fingers region which interacts with the primer strand. This motif is common to several DNA binding proteins and confers a sequence-independent interaction with the DNA backbone [1].
Domain
PF01909Nucleotidyltransferase domain (NTP_transf_2)Nucleotidyltransferase domainMembers of this family belong to a large family of nucleotidyltransferases [1]. This family includes kanamycin nucleotidyltransferase (KNTase) which is a plasmid-coded enzyme responsible for some types of bacterial resistance to aminoglycosides. KNTa ...Members of this family belong to a large family of nucleotidyltransferases [1]. This family includes kanamycin nucleotidyltransferase (KNTase) which is a plasmid-coded enzyme responsible for some types of bacterial resistance to aminoglycosides. KNTase in-activates antibiotics by catalysing the addition of a nucleotidyl group onto the drug.
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
DNA nucleotidylexotransferase
B [auth D],
D [auth U]
5'-D(*AP*AP*AP*AP*AP*C)-3'---
C [auth T]5'-D(*TP*TP*TP*TP*TP*GP*T)-3'---