Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad4ueda1 Alpha and beta proteins (a+b) eIF4e-like eIF4e-like automated matches automated matches HUMAN (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Ad4ueda2 Artifacts Tags Tags Tags N-terminal Tags HUMAN (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyeIF4e-like 8037387 3001871 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AIF4Ee4uedA1 A: a+b two layersX: Translation initiation factor eIF4e and phosphothreonine lyase (From Topology)H: Translation initiation factor eIF4e and phosphothreonine lyase (From Topology)T: Translation initiation factor eIF4e and phosphothreonine lyaseF: IF4EECOD (1.6)
BeIF_4EBPe4uedB1 A: extended segmentsX: 4E-BP2 (From Topology)H: 4E-BP2 (From Topology)T: 4E-BP2F: eIF_4EBPECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.30.760.10 Alpha Beta 2-Layer Sandwich RNA Cap, Translation Initiation Factor Eif4e RNA Cap, Translation Initiation Factor Eif4eCATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF01652Eukaryotic initiation factor 4E (IF4E)Eukaryotic initiation factor 4E- Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
EUKARYOTIC TRANSLATION INITIATION FACTOR 4E
EUKARYOTIC TRANSLATION FACTOR 4E-BINDING PROTEIN 1

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
PharosP06730
PharosQ13541