Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyHydA C-terminal domain-like 8037588 3001861 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyNqo6/HydA N-terminal domain-like 8054419 3002291 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyNqo6/HydA N-terminal domain-like 8054419 3002291 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyHydA C-terminal domain-like 8037588 3001861 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyHydA C-terminal domain-like 8037588 3001861 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyNqo6/HydA N-terminal domain-like 8054419 3002291 SCOP2B (2022-06-29)
D [auth Q]SCOP2B SuperfamilyHydB/Nqo4-like 8037575 3001849 SCOP2B (2022-06-29)
E [auth R]SCOP2B SuperfamilyHydB/Nqo4-like 8037575 3001849 SCOP2B (2022-06-29)
F [auth S]SCOP2B SuperfamilyHydB/Nqo4-like 8037575 3001849 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AOxidored_q6e4upeA2 A: a/b three-layered sandwichesX: Flavodoxin-likeH: Class I glutamine amidotransferase-likeT: CheY-likeF: Oxidored_q6ECOD (1.6)
ANiFe_hyd_SSU_Ce4upeA1 A: few secondary structure elementsX: Fe-S cluster-binding domain in nickel-iron hydrogenase small subunit (From Topology)H: Fe-S cluster-binding domain in nickel-iron hydrogenase small subunit (From Topology)T: Fe-S cluster-binding domain in nickel-iron hydrogenase small subunitF: NiFe_hyd_SSU_CECOD (1.6)
BOxidored_q6e4upeB2 A: a/b three-layered sandwichesX: Flavodoxin-likeH: Class I glutamine amidotransferase-likeT: CheY-likeF: Oxidored_q6ECOD (1.6)
BNiFe_hyd_SSU_Ce4upeB1 A: few secondary structure elementsX: Fe-S cluster-binding domain in nickel-iron hydrogenase small subunit (From Topology)H: Fe-S cluster-binding domain in nickel-iron hydrogenase small subunit (From Topology)T: Fe-S cluster-binding domain in nickel-iron hydrogenase small subunitF: NiFe_hyd_SSU_CECOD (1.6)
COxidored_q6e4upeC2 A: a/b three-layered sandwichesX: Flavodoxin-likeH: Class I glutamine amidotransferase-likeT: CheY-likeF: Oxidored_q6ECOD (1.6)
CNiFe_hyd_SSU_Ce4upeC1 A: few secondary structure elementsX: Fe-S cluster-binding domain in nickel-iron hydrogenase small subunit (From Topology)H: Fe-S cluster-binding domain in nickel-iron hydrogenase small subunit (From Topology)T: Fe-S cluster-binding domain in nickel-iron hydrogenase small subunitF: NiFe_hyd_SSU_CECOD (1.6)
D [auth Q]NiFeSe_Hases_2nde4upeQ2 A: beta meandersX: all-beta domain in nickel-iron hydrogenase large subunit (From Topology)H: all-beta domain in nickel-iron hydrogenase large subunit (From Topology)T: all-beta domain in nickel-iron hydrogenase large subunitF: NiFeSe_Hases_2ndECOD (1.6)
D [auth Q]NiFeSe_Hases_1ste4upeQ4 A: alpha complex topologyX: alpha-helical domain in nickel-iron hydrogenase, large subunit (From Topology)H: alpha-helical domain in nickel-iron hydrogenase, large subunit (From Topology)T: alpha-helical domain in nickel-iron hydrogenase, large subunitF: NiFeSe_Hases_1stECOD (1.6)
D [auth Q]NiFeSe_Hases_3rde4upeQ3 A: a+b two layersX: FAD-linked reductases, C-terminal domain-likeH: Ni-Fe binding domain in nickel-iron hydrogenase large subunit (From Topology)T: Ni-Fe binding domain in nickel-iron hydrogenase large subunitF: NiFeSe_Hases_3rdECOD (1.6)
D [auth Q]NiFeSe_Hases_3rd_1e4upeQ1 A: a+b two layersX: FAD-linked reductases, C-terminal domain-likeH: Ni-Fe binding domain in nickel-iron hydrogenase large subunit (From Topology)T: Ni-Fe binding domain in nickel-iron hydrogenase large subunitF: NiFeSe_Hases_3rd_1ECOD (1.6)
E [auth R]NiFeSe_Hases_2nde4upeR4 A: beta meandersX: all-beta domain in nickel-iron hydrogenase large subunit (From Topology)H: all-beta domain in nickel-iron hydrogenase large subunit (From Topology)T: all-beta domain in nickel-iron hydrogenase large subunitF: NiFeSe_Hases_2ndECOD (1.6)
E [auth R]NiFeSe_Hases_1ste4upeR1 A: alpha complex topologyX: alpha-helical domain in nickel-iron hydrogenase, large subunit (From Topology)H: alpha-helical domain in nickel-iron hydrogenase, large subunit (From Topology)T: alpha-helical domain in nickel-iron hydrogenase, large subunitF: NiFeSe_Hases_1stECOD (1.6)
E [auth R]NiFeSe_Hases_3rde4upeR3 A: a+b two layersX: FAD-linked reductases, C-terminal domain-likeH: Ni-Fe binding domain in nickel-iron hydrogenase large subunit (From Topology)T: Ni-Fe binding domain in nickel-iron hydrogenase large subunitF: NiFeSe_Hases_3rdECOD (1.6)
E [auth R]NiFeSe_Hases_3rd_1e4upeR2 A: a+b two layersX: FAD-linked reductases, C-terminal domain-likeH: Ni-Fe binding domain in nickel-iron hydrogenase large subunit (From Topology)T: Ni-Fe binding domain in nickel-iron hydrogenase large subunitF: NiFeSe_Hases_3rd_1ECOD (1.6)
F [auth S]NiFeSe_Hases_2nde4upeS4 A: beta meandersX: all-beta domain in nickel-iron hydrogenase large subunit (From Topology)H: all-beta domain in nickel-iron hydrogenase large subunit (From Topology)T: all-beta domain in nickel-iron hydrogenase large subunitF: NiFeSe_Hases_2ndECOD (1.6)
F [auth S]NiFeSe_Hases_1ste4upeS1 A: alpha complex topologyX: alpha-helical domain in nickel-iron hydrogenase, large subunit (From Topology)H: alpha-helical domain in nickel-iron hydrogenase, large subunit (From Topology)T: alpha-helical domain in nickel-iron hydrogenase, large subunitF: NiFeSe_Hases_1stECOD (1.6)
F [auth S]NiFeSe_Hases_3rde4upeS3 A: a+b two layersX: FAD-linked reductases, C-terminal domain-likeH: Ni-Fe binding domain in nickel-iron hydrogenase large subunit (From Topology)T: Ni-Fe binding domain in nickel-iron hydrogenase large subunitF: NiFeSe_Hases_3rdECOD (1.6)
F [auth S]NiFeSe_Hases_3rd_1e4upeS2 A: a+b two layersX: FAD-linked reductases, C-terminal domain-likeH: Ni-Fe binding domain in nickel-iron hydrogenase large subunit (From Topology)T: Ni-Fe binding domain in nickel-iron hydrogenase large subunitF: NiFeSe_Hases_3rd_1ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C
PF14720NiFe/NiFeSe hydrogenase small subunit C-terminal (NiFe_hyd_SSU_C)NiFe/NiFeSe hydrogenase small subunit C-terminal- Family
A, B, C
PF01058NADH ubiquinone oxidoreductase, 20 Kd subunit (Oxidored_q6)NADH ubiquinone oxidoreductase, 20 Kd subunit- Family
D [auth Q],
E [auth R],
F [auth S]
PF00374Nickel-dependent hydrogenase (NiFeSe_Hases)Nickel-dependent hydrogenase- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C
NIFE-HYDROGENASE SMALL SUBUNIT
D [auth Q],
E [auth R],
F [auth S]
NICKEL-DEPENDENT HYDROGENASE LARGE SUBUNIT -

Protein Modification Annotation

Modified Residue(s)
ChainResidue(s)Description
D [auth Q],
E [auth R],
F [auth S]
CSX Parent Component: CYS

RESIDAA0451

PSI-MOD :  2'-(S-L-cysteinyl)-6'-hydroxy-L-tryptophan sulfoxide MOD:01380