Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
C [auth L]d4webl1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
A [auth E]HCV_NS1e4webE1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: HCV envelope glycoprotein E2 (From Topology)T: HCV envelope glycoprotein E2F: HCV_NS1ECOD (1.6)
B [auth H]V-set_8e4webH1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_8ECOD (1.6)
B [auth H]C1-set_1e4webH2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)
C [auth L]C1-set_4e4webL2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_4ECOD (1.6)
C [auth L]V-sete4webL1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-setECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
B [auth H]2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
C [auth L]2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)

IMGT Antibody Annotation IMGT Database Homepage

ChainProtein NameDescriptionOrganism NameGene Allele Name(s)Domain Name(s)Receptor TypeReceptor DescriptionProvenance Source
B [auth H]Fab, anti-HCV E2 H-GAMMA-2A Mus musculus (house mouse) IGHV14-3*02, IGHJ4*01, IGHG2A*01, IGHG2A*02 V-DOMAIN VH, C-DOMAIN CH1, C-DOMAIN CH2, C-DOMAIN CH3 IG FAB-GAMMA-2A_KAPPA IMGT (202444-0)
C [auth L]Fab, anti-HCV E2 L-KAPPA Mus musculus (house mouse) IGKV8-24*01, IGKJ2*01, IGKC*01, IGKC*02 V-DOMAIN V-KAPPA, C-DOMAIN C-KAPPA IG FAB-GAMMA-2A_KAPPA IMGT (202444-0)

SAbDab Antibody Annotation SAbDab Database Homepage

ChainChain ClassChain SubclassChain TypeAntigen Name(s) Provenance Source
B [auth H]Heavy ChainIGHV14 -hepatitis c virus envelope glycoprotein 2SAbDab (2024-11-08)
C [auth L]Light ChainIGKV8 Kappahepatitis c virus envelope glycoprotein 2SAbDab (2024-11-08)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A [auth E]hepatitis C virus envelope glycoprotein 2
B [auth H]Mouse Fab Heavy Chain---
C [auth L]Mouse Fab Light Chain---

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A [auth E]IPR002522Hepatitis C virus, Core protein, N-terminalDomain
A [auth E]IPR043128Reverse transcriptase/Diguanylate cyclase domainHomologous Superfamily
A [auth E]IPR054175NS3 RNA helicase, C-terminal helical domainDomain
A [auth E]IPR038568Hepatitis C virus NS5A, 1B domain superfamilyHomologous Superfamily
A [auth E]IPR027417P-loop containing nucleoside triphosphate hydrolaseHomologous Superfamily
A [auth E]IPR009003Peptidase S1, PA clanHomologous Superfamily
A [auth E]IPR001650Helicase, C-terminal domain-likeDomain
A [auth E]IPR014001Helicase superfamily 1/2, ATP-binding domainDomain
A [auth E]IPR002868Hepatitis C virus, Non-structural 5a proteinDomain
A [auth E]IPR038170NS5A domain 1a superfamilyHomologous Superfamily
A [auth E]IPR002518Hepatitis C virus, Non-structural protein NS2Domain
A [auth E]IPR013192Hepatitis C virus, Non-structural 5a protein, domain 1aDomain
A [auth E]IPR002521Hepatitis C virus, Core protein, C-terminalDomain
A [auth E]IPR042209Hepatitis C virus non-structural protein NS2, N-terminal domainHomologous Superfamily
A [auth E]IPR000745Hepatitis C virus, Non-structural protein NS4aDomain
A [auth E]IPR011492Non-structural protein NS3-like, DEAD box helicase, flavivirusDomain
A [auth E]IPR042205Hepatitis C virus non-structural protein NS2, C-terminal domainHomologous Superfamily
A [auth E]IPR002166RNA dependent RNA polymerase, hepatitis C virusFamily
A [auth E]IPR002519Hepatitis C virus, Envelope glycoprotein E1Domain
A [auth E]IPR043502DNA/RNA polymerase superfamilyHomologous Superfamily
A [auth E]IPR044896Hepatitis C virus core protein, chain A superfamilyHomologous Superfamily
A [auth E]IPR024350Hepatitus C virus, Non-structural 5a protein, C-terminalDomain
A [auth E]IPR013193Hepatitis C virus non-structural 5a, 1B domainDomain
A [auth E]IPR004109Hepatitis C virus, NS3 proteaseDomain
A [auth E]IPR049913Hepatitis C virus, p7 channelDomain
A [auth E]IPR002531Hepatitis C virus, Non-structural protein E2/NS1Domain
A [auth E]IPR043504Peptidase S1, PA clan, chymotrypsin-like foldHomologous Superfamily
A [auth E]IPR007094RNA-directed RNA polymerase, catalytic domainDomain
A [auth E]IPR001490Hepatitis C virus, Non-structural protein NS4bDomain