Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APeptidase_M2e5ambA1 A: mixed a+b and a/bX: Zincin-likeH: Metalloproteases (zincins) catalytic domain (From Topology)T: Metalloproteases (zincins) catalytic domainF: Peptidase_M2ECOD (1.6)
BPeptidase_M2e5ambB1 A: mixed a+b and a/bX: Zincin-likeH: Metalloproteases (zincins) catalytic domain (From Topology)T: Metalloproteases (zincins) catalytic domainF: Peptidase_M2ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF01401Angiotensin-converting enzyme (Peptidase_M2)Angiotensin-converting enzyme- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
ANGIOTENSIN-CONVERTING ENZYME
C [auth P],
D [auth Q]
AMYLOID BETA A4 PROTEIN

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B
IPR001548Peptidase M2, peptidyl-dipeptidase AFamily
C [auth P],
D [auth Q]
IPR013803Amyloidogenic glycoprotein, amyloid-beta peptideDomain
C [auth P],
D [auth Q]
IPR008154Amyloidogenic glycoprotein, extracellularDomain
C [auth P],
D [auth Q]
IPR036176E2 domain superfamilyHomologous Superfamily
C [auth P],
D [auth Q]
IPR024329Amyloidogenic glycoprotein, E2 domainDomain
C [auth P],
D [auth Q]
IPR036669Amyloidogenic glycoprotein, copper-binding domain superfamilyHomologous Superfamily
C [auth P],
D [auth Q]
IPR019745Amyloidogenic glycoprotein, intracellular domain, conserved siteConserved Site
C [auth P],
D [auth Q]
IPR011178Amyloidogenic glycoprotein, copper-bindingDomain
C [auth P],
D [auth Q]
IPR037071Amyloidogenic glycoprotein, amyloid-beta peptide superfamilyHomologous Superfamily
C [auth P],
D [auth Q]
IPR020901Proteinase inhibitor I2, Kunitz, conserved siteConserved Site
C [auth P],
D [auth Q]
IPR019744Amyloidogenic glycoprotein, copper-binding domain conserved siteConserved Site
C [auth P],
D [auth Q]
IPR002223Pancreatic trypsin inhibitor Kunitz domainDomain
C [auth P],
D [auth Q]
IPR015849Amyloidogenic glycoprotein, heparin-bindingDomain
C [auth P],
D [auth Q]
IPR036454Amyloidogenic glycoprotein, heparin-binding domain superfamilyHomologous Superfamily
C [auth P],
D [auth Q]
IPR011993PH-like domain superfamilyHomologous Superfamily
C [auth P],
D [auth Q]
IPR019543Beta-amyloid precursor protein C-terminalDomain
C [auth P],
D [auth Q]
IPR036880Pancreatic trypsin inhibitor Kunitz domain superfamilyHomologous Superfamily
C [auth P],
D [auth Q]
IPR008155Amyloidogenic glycoproteinFamily

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
A, B
PharosP12821
C [auth P],
D [auth Q]
PharosP05067