5BQX
Crystal structure of human STING in complex with 3'2'-cGAMP
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d5bqxa_ | Alpha and beta proteins (a+b) | STING C-terminal-like | STING, TM173 CTD-like | Tyrosinase cofactor MelC1 | Tyrosinase cofactor MelC1 | Human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Domain Annotation: ECOD Classification ECOD Database Homepage
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 1.20.5.5200 | Mainly Alpha | Up-down Bundle | Single alpha-helices involved in coiled-coils or other helix-helix interfaces | CATH (4.3.0) | |
A | 3.40.50.12100 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Stimulator of interferon genes protein | CATH (4.3.0) |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR029158 | Stimulator of interferon genes protein | Family | |
IPR047191 | Stimulator of interferon genes protein, C-terminal | Domain | |
IPR038623 | Stimulator of interferon genes protein, C-terminal domain superfamily | Homologous Superfamily |