X-ray structure of the Fab fragment of 8B6, a murine monoclonal antibody specific for the human serotonin transporter
External Resource: Annotation
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
A | V-set_8 | e5i66A2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set_8 | ECOD (1.6) |
A | C1-set_1 | e5i66A1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: C1-set_1 | ECOD (1.6) |
B | C1-set_4 | e5i66B1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: C1-set_4 | ECOD (1.6) |
B | V-set | e5i66B2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set | ECOD (1.6) |
Chain | Protein Name | Description | Organism Name | Gene Allele Name(s) | Domain Name(s) | Receptor Type | Receptor Description | Provenance Source |
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| 8B6 Fab | VH-CH1 | Mus musculus (house mouse) | IGHV1-26*01, IGHJ2*01, IGHG2B*02 | V-DOMAIN VH, C-DOMAIN CH1 | IG | FAB-GAMMA-2B_KAPPA | IMGT (202445-0) |
| 8B6 Fab | L-KAPPA | Mus musculus (house mouse) | IGKV6-17*01, IGKJ1*01, IGKJ2*01, IGKC*01, IGKC*02 | V-DOMAIN V-KAPPA, C-DOMAIN C-KAPPA | IG | FAB-GAMMA-2B_KAPPA | IMGT (202445-0) |
Chain | Chain Class | Chain Subclass | Chain Type | Antigen Name(s) | Provenance Source |
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| Heavy Chain | IGHV1 | - | - | SAbDab (2024-11-15) |
| Light Chain | IGKV6 | Kappa | - | SAbDab (2024-11-15) |