Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ANeur_chan_LBDe5kxiA2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Nicotinic receptor ligand binding domain-like (From Topology)T: Nicotinic receptor ligand binding domain-likeF: Neur_chan_LBDECOD (1.6)
ANeur_chan_membe5kxiA1 A: alpha bundlesX: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)T: Neurotransmitter-gated ion-channel transmembrane poreF: Neur_chan_membECOD (1.6)
DNeur_chan_LBDe5kxiD1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Nicotinic receptor ligand binding domain-like (From Topology)T: Nicotinic receptor ligand binding domain-likeF: Neur_chan_LBDECOD (1.6)
DNeur_chan_membe5kxiD2 A: alpha bundlesX: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)T: Neurotransmitter-gated ion-channel transmembrane poreF: Neur_chan_membECOD (1.6)
BNeur_chan_LBDe5kxiB2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Nicotinic receptor ligand binding domain-like (From Topology)T: Nicotinic receptor ligand binding domain-likeF: Neur_chan_LBDECOD (1.6)
BNeur_chan_membe5kxiB1 A: alpha bundlesX: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)T: Neurotransmitter-gated ion-channel transmembrane poreF: Neur_chan_membECOD (1.6)
ENeur_chan_LBDe5kxiE2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Nicotinic receptor ligand binding domain-like (From Topology)T: Nicotinic receptor ligand binding domain-likeF: Neur_chan_LBDECOD (1.6)
ENeur_chan_membe5kxiE1 A: alpha bundlesX: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)T: Neurotransmitter-gated ion-channel transmembrane poreF: Neur_chan_membECOD (1.6)
CNeur_chan_LBDe5kxiC1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Nicotinic receptor ligand binding domain-like (From Topology)T: Nicotinic receptor ligand binding domain-likeF: Neur_chan_LBDECOD (1.6)
CNeur_chan_membe5kxiC2 A: alpha bundlesX: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)H: Neurotransmitter-gated ion-channel transmembrane pore (From Topology)T: Neurotransmitter-gated ion-channel transmembrane poreF: Neur_chan_membECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, D
PF02932Neurotransmitter-gated ion-channel transmembrane region (Neur_chan_memb)Neurotransmitter-gated ion-channel transmembrane region- Family
A, D
PF02931Neurotransmitter-gated ion-channel ligand binding domain (Neur_chan_LBD)Neurotransmitter-gated ion-channel ligand binding domain- Family
B, C, E
PF02932Neurotransmitter-gated ion-channel transmembrane region (Neur_chan_memb)Neurotransmitter-gated ion-channel transmembrane region- Family
B, C, E
PF02931Neurotransmitter-gated ion-channel ligand binding domain (Neur_chan_LBD)Neurotransmitter-gated ion-channel ligand binding domain- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, D
Neuronal acetylcholine receptor subunit alpha-4
B, C, E
Neuronal acetylcholine receptor subunit beta-2

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
A, D
PharosP43681
B, C, E
PharosP17787

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

ChainsExternal LinkComment
A, B, C, D, E
PDBTMAnnotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage