5MEX

Sulphotransferase-18 from Arabidopsis thaliana in complex with 3'-phosphoadenosine 5'-phosphate (PAP)and sinigrin

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Sulfotransfer_1	e5mexA1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Sulfotransfer_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.300	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	P-loop containing nucleotide triphosphate hydrolases	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00685	Sulfotransferase domain (Sulfotransfer_1)	Sulfotransferase domain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Cytosolic sulfotransferase 18	desulfoglucosinolate sulfotransferase activity 8-methylthiooctyl-desulfoglucosinolate sulfotransferase activity transferase activity, transferring sulphur-containing groups sulfotransferase activity transferase activity catalytic activity 4-methylthiobutyl-desulfoglucosinolate sulfotransferase activity indol-3-yl-methyl-desulfoglucosinolate sulfotransferase activity 5-methylthiopentyl-desulfoglucosinolate sulfotransferase activity 7-methylthioheptyl-desulfoglucosinolate sulfotransferase activity 3-methylthiopropyl-desulfoglucosinolate sulfotransferase activity	carbohydrate derivative biosynthetic process glycosyl compound metabolic process glycosyl compound biosynthetic process oxoacid metabolic process glucosinolate metabolic process cellular biosynthetic process cellular metabolic process carbohydrate derivative metabolic process organic acid metabolic process sulfur compound biosynthetic process biosynthetic process glucosinolate biosynthetic process S-glycoside metabolic process S-glycoside biosynthetic process carbohydrate derivative biosynthetic process glycosyl compound metabolic process glycosyl compound biosynthetic process oxoacid metabolic process glucosinolate metabolic process cellular biosynthetic process cellular metabolic process carbohydrate derivative metabolic process organic acid metabolic process sulfur compound biosynthetic process biosynthetic process glucosinolate biosynthetic process S-glycoside metabolic process S-glycoside biosynthetic process sulfur compound metabolic process metabolic process cellular process small molecule metabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR000863	Sulfotransferase domain	Domain
A	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.