5MSD
Structure of the A domain of carboxylic acid reductase (CAR) from Nocardia iowensis in complex with AMP and benzoic acid
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | AMP-binding_3rd | e5msdA1 | A: beta barrels | X: beta-barrel domain in acetyl-CoA synthetase-like proteins (From Topology) | H: beta-barrel domain in acetyl-CoA synthetase-like proteins (From Topology) | T: beta-barrel domain in acetyl-CoA synthetase-like proteins | F: AMP-binding_3rd | ECOD (1.6) |
A | AMP-binding_C | e5msdA4 | A: a+b two layers | X: Alpha-lytic protease prodomain-like | H: a+b domain in acetyl-CoA synthetase-like proteins (From Topology) | T: a+b domain in acetyl-CoA synthetase-like proteins | F: AMP-binding_C | ECOD (1.6) |
A | AMP-binding_1st | e5msdA3 | A: a/b three-layered sandwiches | X: Rossmann-like domain in Acetyl-CoA synthetase-like proteins (From Topology) | H: Rossmann-like domain in Acetyl-CoA synthetase-like proteins (From Topology) | T: Rossmann-like domain in Acetyl-CoA synthetase-like proteins | F: AMP-binding_1st | ECOD (1.6) |
A | AMP-binding_2nd | e5msdA2 | A: a/b three-layered sandwiches | X: Rossmann-like domain in Acetyl-CoA synthetase-like proteins (From Topology) | H: Rossmann-like domain in Acetyl-CoA synthetase-like proteins (From Topology) | T: Rossmann-like domain in Acetyl-CoA synthetase-like proteins | F: AMP-binding_2nd | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00501 | AMP-binding enzyme (AMP-binding) | AMP-binding enzyme | - | Family |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR009081 | Phosphopantetheine binding ACP domain | Domain | |
IPR046407 | Carboxylic acid reductase | Family | |
IPR020845 | AMP-binding, conserved site | Conserved Site | |
IPR013120 | Fatty acyl-coenzyme A reductase-like, NAD-binding domain | Domain | |
IPR042099 | ANL, N-terminal domain | Homologous Superfamily | |
IPR036291 | NAD(P)-binding domain superfamily | Homologous Superfamily | |
IPR020806 | Polyketide synthase, phosphopantetheine-binding domain | Domain | |
IPR036736 | ACP-like superfamily | Homologous Superfamily | |
IPR000873 | AMP-dependent synthetase/ligase domain | Domain | |
IPR010080 | Thioester reductase-like domain | Domain |