Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
A [auth B]DNA_primase_Se5op0B1 A: a+b complex topologyX: Prim-pol domain (From Topology)H: Prim-pol domain (From Topology)T: Prim-pol domainF: DNA_primase_SECOD (1.6)
B [auth A]DNA_primase_Se5op0A1 A: a+b complex topologyX: Prim-pol domain (From Topology)H: Prim-pol domain (From Topology)T: Prim-pol domainF: DNA_primase_SECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A [auth B],
B [auth A]
PF21686LigD, primase-polymerase domain (LigD_Prim-Pol)LigD, primase-polymerase domainThis entry represents the primase-polymerase domain (Prim-Pol) of bacterial LigD proteins, such as LigD from Pseudomonas aeruginosa and Mycobacterium tuberculosis. LigD, together with Ku protein, is required for nonhomologous end-joining (NHEJ)-media ...This entry represents the primase-polymerase domain (Prim-Pol) of bacterial LigD proteins, such as LigD from Pseudomonas aeruginosa and Mycobacterium tuberculosis. LigD, together with Ku protein, is required for nonhomologous end-joining (NHEJ)-mediated repair of DNA double-strand breaks (DSB). This domain belongs to the archaeal/eukaryal primase (AEP) superfamily and mediates several nucleotidyl transferase activities, including DNA-dependent RNA primase, terminal transferase and DNA-dependent DNA/RNA gap-filling polymerase activities [1-5].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A [auth B],
B [auth A]
DNA polymerase LigD, polymerase domain - -