5TCM

First Bromodomain from Leishmania donovani LdBPK.091320 complexed with BI-2536

External Resource: Annotation


Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ABromodomaine5tcmA1 A: alpha bundlesX: Bromodomain-likeH: Bromodomain (From Topology)T: BromodomainF: BromodomainECOD (1.6)
CBromodomaine5tcmC1 A: alpha bundlesX: Bromodomain-likeH: Bromodomain (From Topology)T: BromodomainF: BromodomainECOD (1.6)
BBromodomaine5tcmB1 A: alpha bundlesX: Bromodomain-likeH: Bromodomain (From Topology)T: BromodomainF: BromodomainECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A1.20.920.10 Mainly Alpha Up-down Bundle Histone Acetyltransferase Chain ACATH (4.3.0)
C1.20.920.10 Mainly Alpha Up-down Bundle Histone Acetyltransferase Chain ACATH (4.3.0)
B1.20.920.10 Mainly Alpha Up-down Bundle Histone Acetyltransferase Chain ACATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C
PF00439Bromodomain (Bromodomain)BromodomainBromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine [3].Domain

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C
IPR051831Bromodomain-containingFamily
A, B, C
IPR001487BromodomainDomain
A, B, C
IPR036427Bromodomain-like superfamilyHomologous Superfamily