Crystal structure of the core catalytic domain of human inositol phosphate multikinase
External Resource: Annotation
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
A | IPK | e5w2gA1 | A: a+b complex topology | X: Protein kinase/SAICAR synthase/ATP-grasp (From Homology) | H: Protein kinase/SAICAR synthase/ATP-grasp | T: SAICAR synthase | F: IPK | ECOD (1.6) |
Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
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| Inositol polyphosphate multikinase,Inositol polyphosphate multikinase | - kinase activity
- transferase activity
- inositol-1,4,5-trisphosphate 3-kinase activity
- inositol phosphate kinase activity
- inositol trisphosphate kinase activity
- catalytic activity
- phosphotransferase activity, alcohol group as acceptor
- transferase activity, transferring phosphorus-containing groups
- binding
- adenyl ribonucleotide binding
- nucleotide binding
- purine ribonucleotide binding
- purine ribonucleoside triphosphate binding
- nucleoside phosphate binding
- ion binding
- purine nucleotide binding
- organic cyclic compound binding
- anion binding
- adenyl nucleotide binding
- ATP binding
- heterocyclic compound binding
- carbohydrate derivative binding
- ribonucleotide binding
- small molecule binding
- inositol tetrakisphosphate kinase activity
- inositol-1,3,4,5-tetrakisphosphate 6-kinase activity
- inositol-1,3,4,6-tetrakisphosphate 5-kinase activity
- inositol pentakisphosphate kinase activity
- inositol-1,2,3,4,6-pentakisphosphate 5-kinase activity
- phosphatidylinositol kinase activity
- lipid kinase activity
- 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity
- flavonoid binding
- inositol-1,4,5-trisphosphate 6-kinase activity
- inositol-1,4,5,6-tetrakisphosphate 3-kinase activity
- cation binding
- metal ion binding
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Chains | Drug Target   | Associated Disease |
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| Pharos:  Q8NFU5 | |