5XK9

Crystal structure of Isosesquilavandulyl Diphosphate Synthase from Streptomyces sp. strain CNH-189 in complex with GSPP and DMAPP

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d5xk9a_	Alpha and beta proteins (a/b)	Undecaprenyl diphosphate synthase	Undecaprenyl diphosphate synthase	automated matches	automated matches	(Streptomyces sp. CNH189 ) [TaxId: 1136432 ],	SCOPe (2.08)
B	d5xk9b1	Alpha and beta proteins (a/b)	Undecaprenyl diphosphate synthase	Undecaprenyl diphosphate synthase	automated matches	automated matches	(Streptomyces sp. CNH189 ) [TaxId: 1136432 ],	SCOPe (2.08)
B	d5xk9b2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Streptomyces sp. CNH189 ) [TaxId: 1136432 ],	SCOPe (2.08)
C	d5xk9c1	Alpha and beta proteins (a/b)	Undecaprenyl diphosphate synthase	Undecaprenyl diphosphate synthase	automated matches	automated matches	(Streptomyces sp. CNH189 ) [TaxId: 1136432 ],	SCOPe (2.08)
C	d5xk9c2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Streptomyces sp. CNH189 ) [TaxId: 1136432 ],	SCOPe (2.08)
D	d5xk9d_	Alpha and beta proteins (a/b)	Undecaprenyl diphosphate synthase	Undecaprenyl diphosphate synthase	automated matches	automated matches	(Streptomyces sp. CNH189 ) [TaxId: 1136432 ],	SCOPe (2.08)
E	d5xk9e_	Alpha and beta proteins (a/b)	Undecaprenyl diphosphate synthase	Undecaprenyl diphosphate synthase	automated matches	automated matches	(Streptomyces sp. CNH189 ) [TaxId: 1136432 ],	SCOPe (2.08)
F	d5xk9f1	Alpha and beta proteins (a/b)	Undecaprenyl diphosphate synthase	Undecaprenyl diphosphate synthase	automated matches	automated matches	(Streptomyces sp. CNH189 ) [TaxId: 1136432 ],	SCOPe (2.08)
F	d5xk9f2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Streptomyces sp. CNH189 ) [TaxId: 1136432 ],	SCOPe (2.08)
G	d5xk9g1	Alpha and beta proteins (a/b)	Undecaprenyl diphosphate synthase	Undecaprenyl diphosphate synthase	automated matches	automated matches	(Streptomyces sp. CNH189 ) [TaxId: 1136432 ],	SCOPe (2.08)
G	d5xk9g2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Streptomyces sp. CNH189 ) [TaxId: 1136432 ],	SCOPe (2.08)
H	d5xk9h_	Alpha and beta proteins (a/b)	Undecaprenyl diphosphate synthase	Undecaprenyl diphosphate synthase	automated matches	automated matches	(Streptomyces sp. CNH189 ) [TaxId: 1136432 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Undecaprenyl diphosphate synthase	8067728	3000594	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Undecaprenyl diphosphate synthase	8067728	3000594	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Undecaprenyl diphosphate synthase	8067728	3000594	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Undecaprenyl diphosphate synthase	8067728	3000594	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Undecaprenyl diphosphate synthase	8067728	3000594	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Undecaprenyl diphosphate synthase	8067728	3000594	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Undecaprenyl diphosphate synthase	8067728	3000594	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Undecaprenyl diphosphate synthase	8067728	3000594	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Prenyltransf	e5xk9A1	A: a/b three-layered sandwiches	X: Undecaprenyl diphosphate synthase (From Topology)	H: Undecaprenyl diphosphate synthase (From Topology)	T: Undecaprenyl diphosphate synthase	F: Prenyltransf	ECOD (1.6)
B	Prenyltransf	e5xk9B1	A: a/b three-layered sandwiches	X: Undecaprenyl diphosphate synthase (From Topology)	H: Undecaprenyl diphosphate synthase (From Topology)	T: Undecaprenyl diphosphate synthase	F: Prenyltransf	ECOD (1.6)
C	Prenyltransf	e5xk9C1	A: a/b three-layered sandwiches	X: Undecaprenyl diphosphate synthase (From Topology)	H: Undecaprenyl diphosphate synthase (From Topology)	T: Undecaprenyl diphosphate synthase	F: Prenyltransf	ECOD (1.6)
D	Prenyltransf	e5xk9D1	A: a/b three-layered sandwiches	X: Undecaprenyl diphosphate synthase (From Topology)	H: Undecaprenyl diphosphate synthase (From Topology)	T: Undecaprenyl diphosphate synthase	F: Prenyltransf	ECOD (1.6)
E	Prenyltransf	e5xk9E1	A: a/b three-layered sandwiches	X: Undecaprenyl diphosphate synthase (From Topology)	H: Undecaprenyl diphosphate synthase (From Topology)	T: Undecaprenyl diphosphate synthase	F: Prenyltransf	ECOD (1.6)
F	Prenyltransf	e5xk9F1	A: a/b three-layered sandwiches	X: Undecaprenyl diphosphate synthase (From Topology)	H: Undecaprenyl diphosphate synthase (From Topology)	T: Undecaprenyl diphosphate synthase	F: Prenyltransf	ECOD (1.6)
G	Prenyltransf	e5xk9G1	A: a/b three-layered sandwiches	X: Undecaprenyl diphosphate synthase (From Topology)	H: Undecaprenyl diphosphate synthase (From Topology)	T: Undecaprenyl diphosphate synthase	F: Prenyltransf	ECOD (1.6)
H	Prenyltransf	e5xk9H1	A: a/b three-layered sandwiches	X: Undecaprenyl diphosphate synthase (From Topology)	H: Undecaprenyl diphosphate synthase (From Topology)	T: Undecaprenyl diphosphate synthase	F: Prenyltransf	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H	PF01255	Putative undecaprenyl diphosphate synthase (Prenyltransf)	Putative undecaprenyl diphosphate synthase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H	Undecaprenyl diphosphate synthase	polyprenyltransferase activity prenyltransferase activity transferase activity transferase activity, transferring alkyl or aryl (other than methyl) groups catalytic activity cation binding ion binding binding metal ion binding small molecule binding	polyprenol metabolic process polyprenol biosynthetic process small molecule biosynthetic process isoprenoid biosynthetic process cellular biosynthetic process organic hydroxy compound metabolic process cellular metabolic process lipid biosynthetic process alcohol metabolic process primary metabolic process biosynthetic process organic hydroxy compound biosynthetic process cellular lipid metabolic process alcohol biosynthetic process polyprenol metabolic process polyprenol biosynthetic process small molecule biosynthetic process isoprenoid biosynthetic process cellular biosynthetic process organic hydroxy compound metabolic process cellular metabolic process lipid biosynthetic process alcohol metabolic process primary metabolic process biosynthetic process organic hydroxy compound biosynthetic process cellular lipid metabolic process alcohol biosynthetic process small molecule metabolic process metabolic process cellular process isoprenoid metabolic process lipid metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H	IPR036424	Decaprenyl diphosphate synthase-like superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H	IPR001441	Decaprenyl diphosphate synthase-like	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.