Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AACT_5e5yppA1 A: a+b two layersX: Alpha-beta plaitsH: ACT-like (From Topology)T: ACT-likeF: ACT_5ECOD (1.6)
BACT_5e5yppB1 A: a+b two layersX: Alpha-beta plaitsH: ACT-like (From Topology)T: ACT-likeF: ACT_5ECOD (1.6)
CACT_5e5yppC1 A: a+b two layersX: Alpha-beta plaitsH: ACT-like (From Topology)T: ACT-likeF: ACT_5ECOD (1.6)
DACT_5e5yppD1 A: a+b two layersX: Alpha-beta plaitsH: ACT-like (From Topology)T: ACT-likeF: ACT_5ECOD (1.6)
EACT_5e5yppE1 A: a+b two layersX: Alpha-beta plaitsH: ACT-like (From Topology)T: ACT-likeF: ACT_5ECOD (1.6)
FACT_5e5yppF1 A: a+b two layersX: Alpha-beta plaitsH: ACT-like (From Topology)T: ACT-likeF: ACT_5ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.30.70.260 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits ACT domainCATH (4.3.0)
B3.30.70.260 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits ACT domainCATH (4.3.0)
C3.30.70.260 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits ACT domainCATH (4.3.0)
D3.30.70.260 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits ACT domainCATH (4.3.0)
E3.30.70.260 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits ACT domainCATH (4.3.0)
F3.30.70.260 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits ACT domainCATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D, E
PF01842ACT domain (ACT)ACT domainThis family of domains generally have a regulatory role. ACT domains are linked to a wide range of metabolic enzymes that are regulated by amino acid concentration. Pairs of ACT domains bind specifically to a particular amino acid leading to regulati ...This family of domains generally have a regulatory role. ACT domains are linked to a wide range of metabolic enzymes that are regulated by amino acid concentration. Pairs of ACT domains bind specifically to a particular amino acid leading to regulation of the linked enzyme. The ACT domain is found in: D-3-phosphoglycerate dehydrogenase EC:1.1.1.95 Swiss:P08328, which is inhibited by serine [1]. Aspartokinase EC:2.7.2.4 Swiss:P53553, which is regulated by lysine. Acetolactate synthase small regulatory subunit Swiss:P00894, which is inhibited by valine. Phenylalanine-4-hydroxylase EC:1.14.16.1 Swiss:P00439, which is regulated by phenylalanine. Prephenate dehydrogenase EC:4.2.1.51 Swiss:P21203. formyltetrahydrofolate deformylase EC:3.5.1.10, Swiss:P37051, which is activated by methionine and inhibited by glycine. GTP pyrophosphokinase EC:2.7.6.5 Swiss:P11585
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D, E
Acetolactate synthase isozyme 1 small subunit

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D, E
IPR039557AHAS, ACT domainDomain
A, B, C, D, E
IPR004789Acetolactate synthase, small subunitFamily
A, B, C, D, E
IPR045865ACT-like domainHomologous Superfamily
A, B, C, D, E
IPR002912ACT domainDomain