Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2 FamilyD-lactate/D-glycerate dehydrogenase-like 8078030 4000099 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyD-2-hydroxyacid dehydrogenase-like 8078031 3000044 SCOP2 (2022-06-29)
BSCOP2B SuperfamilyD-2-hydroxyacid dehydrogenase-like 8078031 3000044 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyD-2-hydroxyacid dehydrogenase-like 8078031 3000044 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyD-2-hydroxyacid dehydrogenase-like 8078031 3000044 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
A2-Hacid_dh_Ce5z21A2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: 2-Hacid_dh_CECOD (1.6)
A2-Hacid_dhe5z21A1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: Formate/glycerate dehydrogenase catalytic domain-likeF: 2-Hacid_dhECOD (1.6)
B2-Hacid_dh_Ce5z21B1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: 2-Hacid_dh_CECOD (1.6)
B2-Hacid_dhe5z21B2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: Formate/glycerate dehydrogenase catalytic domain-likeF: 2-Hacid_dhECOD (1.6)
C2-Hacid_dh_Ce5z21C2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: 2-Hacid_dh_CECOD (1.6)
C2-Hacid_dhe5z21C1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: Formate/glycerate dehydrogenase catalytic domain-likeF: 2-Hacid_dhECOD (1.6)
D2-Hacid_dh_Ce5z21D2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: 2-Hacid_dh_CECOD (1.6)
D2-Hacid_dhe5z21D1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: Formate/glycerate dehydrogenase catalytic domain-likeF: 2-Hacid_dhECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D
PF02826D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain (2-Hacid_dh_C)D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domainThis domain is inserted into the catalytic domain, the large dehydrogenase and D-lactate dehydrogenase families in SCOP. N-terminal portion of which is represented by family Pfam:PF00389.Domain
A, B, C, D
PF00389D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (2-Hacid_dh)D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domainThis family represents the largest portion of the catalytic domain of 2-hydroxyacid dehydrogenases as the NAD binding domain is inserted within the structural domain.Domain