6FHZ

Inward-facing conformation of a multidrug resistance MATE family transporter of the MOP superfamily.

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: OPM
Membrane Protein Annotation: PDBTM
Membrane Protein Annotation: MemProtMD
Membrane Protein Annotation: mpstruc

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	MatE	e6fhzA2	A: alpha bundles	X: Type II ABC exporter transmembrane domain fold	H: Multidrug and toxic compound extrusion (MATE) transporter (From Topology)	T: Multidrug and toxic compound extrusion (MATE) transporter	F: MatE	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF01554	MatE (MatE)	MatE	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Putative MOP flippase	xenobiotic transmembrane transporter activity transporter activity transmembrane transporter activity antiporter activity active transmembrane transporter activity secondary active transmembrane transporter activity	-	cell periphery plasma membrane membrane cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR002528	Multi antimicrobial extrusion protein	Family
A	IPR048279	Multidrug resistance protein MdtK-like	Family
A	IPR052031	Membrane Transporter and Flippase	Family

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A	OPM	Transmembrane	Alpha-helical polytopic	Multidrug/Oligosaccharidyl-lipid superfamily	Multi antimicrobial extrusion (MATE) family

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A	MemProtMD	Annotated as membrane protein by MemProtMD

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A	mpstruc	TRANSMEMBRANE PROTEINS: ALPHA-HELICAL	Multi-Drug Efflux Transporters	Multidrug and Toxin Compound Extrusion (MATE) transporter, inward-facing conformation, lipidic cubic phase

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.