6GJU
human NBD1 of CFTR in complex with nanobodies T2a and T4
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | d6gjub1 | All beta proteins | Immunoglobulin-like beta-sandwich | Immunoglobulin | automated matches | automated matches | llama (Lama glama ) [TaxId: 9844 ], | SCOPe (2.08) |
B | d6gjub2 | Artifacts | Tags | Tags | Tags | N-terminal Tags | llama (Lama glama ) [TaxId: 9844 ], | SCOPe (2.08) |
C | d6gjuc1 | All beta proteins | Immunoglobulin-like beta-sandwich | Immunoglobulin | automated matches | automated matches | llama (Lama glama ) [TaxId: 9844 ], | SCOPe (2.08) |
C | d6gjuc2 | Artifacts | Tags | Tags | Tags | N-terminal Tags | llama (Lama glama ) [TaxId: 9844 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | ABC_tran_1 | e6gjuA1 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: ABC_tran_1 | ECOD (1.6) |
B | V-set_8 | e6gjuB1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set_8 | ECOD (1.6) |
C | V-set_8 | e6gjuC1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set_8 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.40.50.300 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | P-loop containing nucleotide triphosphate hydrolases | CATH (utative) |
SAbDab Antibody Annotation SAbDab Database Homepage
Chain | Chain Class | Chain Subclass | Chain Type | Antigen Name(s) | Provenance Source |
---|---|---|---|---|---|
Heavy Chain | IGHV1 | - | cystic fibrosis transmembrane conductance regulator | SAbDab (2024-11-08) | |
Heavy Chain | IGHV1 | - | cystic fibrosis transmembrane conductance regulator | SAbDab (2024-11-08) |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR047082 | Cystic fibrosis transmembrane conductance regulator, ATP-binding cassette domain 1 | Domain | |
IPR003439 | ABC transporter-like, ATP-binding domain | Domain | |
IPR009147 | Cystic fibrosis transmembrane conductance regulator | Family | |
IPR025837 | CFTR regulator domain | Domain | |
IPR027417 | P-loop containing nucleoside triphosphate hydrolase | Homologous Superfamily | |
IPR003593 | AAA+ ATPase domain | Domain | |
IPR011527 | ABC transporter type 1, transmembrane domain | Domain | |
IPR017871 | ABC transporter-like, conserved site | Conserved Site | |
IPR036640 | ABC transporter type 1, transmembrane domain superfamily | Homologous Superfamily | |
IPR050173 | ATP-binding cassette transporter C-like | Family |