Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AATP-grasp_2e6hxiA2 A: a+b complex topologyX: Protein kinase/SAICAR synthase/ATP-grasp (From Homology)H: Protein kinase/SAICAR synthase/ATP-graspT: ATP-graspF: ATP-grasp_2ECOD (1.6)
ACitrate_binde6hxiA1 A: a/b three-layered sandwichesX: Flavodoxin-likeH: Succinyl-CoA synthetase domains (From Topology)T: Succinyl-CoA synthetase domainsF: Citrate_bindECOD (1.6)
CATP-grasp_2e6hxiC1 A: a+b complex topologyX: Protein kinase/SAICAR synthase/ATP-grasp (From Homology)H: Protein kinase/SAICAR synthase/ATP-graspT: ATP-graspF: ATP-grasp_2ECOD (1.6)
CCitrate_binde6hxiC2 A: a/b three-layered sandwichesX: Flavodoxin-likeH: Succinyl-CoA synthetase domains (From Topology)T: Succinyl-CoA synthetase domainsF: Citrate_bindECOD (1.6)
BCitrate_synte6hxiB3 A: alpha complex topologyX: Citrate synthase-likeH: Citrate synthase (From Topology)T: Citrate synthaseF: Citrate_syntECOD (1.6)
BCoA_bindinge6hxiB1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: CoA_bindingECOD (1.6)
BSucc_CoA_lige6hxiB2 A: a/b three-layered sandwichesX: Flavodoxin-likeH: Succinyl-CoA synthetase domains (From Topology)T: Succinyl-CoA synthetase domainsF: Succ_CoA_ligECOD (1.6)
DCitrate_synte6hxiD1 A: alpha complex topologyX: Citrate synthase-likeH: Citrate synthase (From Topology)T: Citrate synthaseF: Citrate_syntECOD (1.6)
DCoA_bindinge6hxiD3 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: CoA_bindingECOD (1.6)
DSucc_CoA_lige6hxiD2 A: a/b three-layered sandwichesX: Flavodoxin-likeH: Succinyl-CoA synthetase domains (From Topology)T: Succinyl-CoA synthetase domainsF: Succ_CoA_ligECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.30.470.110 Alpha Beta 2-Layer Sandwich D-amino Acid Aminotransferase Chain A, domain 1CATH (utative)
A3.40.50.261 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold Succinyl-CoA synthetase domainsCATH (utative)
C3.30.1490.20 Alpha Beta 2-Layer Sandwich Dna Ligase domain 1CATH (utative)
C3.40.50.261 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold Succinyl-CoA synthetase domainsCATH (utative)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, C
PF08442ATP-grasp domain (ATP-grasp_2)ATP-grasp domain- Domain
A, C
PF16114ATP citrate lyase citrate-binding (Citrate_bind)ATP citrate lyase citrate-bindingThis is the citrate-binding domain of ATP citrate lyase. This domain has a Rossmann fold [1].Domain
B, D
PF00549CoA-ligase (Ligase_CoA)CoA-ligaseThis family includes the CoA ligases Succinyl-CoA synthetase alpha and beta chains, malate CoA ligase and ATP-citrate lyase. Some members of the family utilise ATP others use GTP.Domain
B, D
PF00285Citrate synthase, C-terminal domain (Citrate_synt)Citrate synthase, C-terminal domainThis is the long, C-terminal part of the enzyme.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, C
Citrate lyase, subunit 1
B, D
Succinyl-CoA ligase (ADP-forming) subunit alpha