Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad6rjca1 Alpha and beta proteins (a/b) Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) TK-like PP module automated matches (Escherichia coli K-12 ) [TaxId: 83333 ], SCOPe (2.08)
Ad6rjca2 Alpha and beta proteins (a/b) Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) automated matches automated matches (Escherichia coli K-12 ) [TaxId: 83333 ], SCOPe (2.08)
Ad6rjca3 Alpha and beta proteins (a/b) TK C-terminal domain-like TK C-terminal domain-like automated matches automated matches (Escherichia coli K-12 ) [TaxId: 83333 ], SCOPe (2.08)
Ad6rjca4 Artifacts Tags Tags Tags C-terminal Tags (Escherichia coli K-12 ) [TaxId: 83333 ], SCOPe (2.08)
Bd6rjcb1 Alpha and beta proteins (a/b) Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) TK-like PP module automated matches (Escherichia coli K-12 ) [TaxId: 83333 ], SCOPe (2.08)
Bd6rjcb2 Alpha and beta proteins (a/b) Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) automated matches automated matches (Escherichia coli K-12 ) [TaxId: 83333 ], SCOPe (2.08)
Bd6rjcb3 Alpha and beta proteins (a/b) TK C-terminal domain-like TK C-terminal domain-like automated matches automated matches (Escherichia coli K-12 ) [TaxId: 83333 ], SCOPe (2.08)
Bd6rjcb4 Artifacts Tags Tags Tags C-terminal Tags (Escherichia coli K-12 ) [TaxId: 83333 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyThiamin diphosphate-binding fold (THDP-binding) 8036682 3001790 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyThiamin diphosphate-binding fold (THDP-binding) 8036680 3001790 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyTK C-terminal domain-like 8036683 3000424 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyThiamin diphosphate-binding fold (THDP-binding) 8036682 3001790 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyTK C-terminal domain-like 8036683 3000424 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyThiamin diphosphate-binding fold (THDP-binding) 8036680 3001790 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ATransketolase_C_1e6rjcA3 A: a/b three-layered sandwichesX: TK C-terminal domain-like (From Topology)H: TK C-terminal domain-like (From Topology)T: TK C-terminal domain-likeF: Transketolase_C_1ECOD (1.6)
ATransketolase_Ne6rjcA2 A: a/b three-layered sandwichesX: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)T: Thiamin diphosphate-binding fold (THDP-binding)F: Transketolase_NECOD (1.6)
ATransket_pyre6rjcA1 A: a/b three-layered sandwichesX: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)T: Thiamin diphosphate-binding fold (THDP-binding)F: Transket_pyrECOD (1.6)
BTransketolase_C_1e6rjcB2 A: a/b three-layered sandwichesX: TK C-terminal domain-like (From Topology)H: TK C-terminal domain-like (From Topology)T: TK C-terminal domain-likeF: Transketolase_C_1ECOD (1.6)
BTransketolase_Ne6rjcB1 A: a/b three-layered sandwichesX: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)T: Thiamin diphosphate-binding fold (THDP-binding)F: Transketolase_NECOD (1.6)
BTransket_pyre6rjcB3 A: a/b three-layered sandwichesX: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology)T: Thiamin diphosphate-binding fold (THDP-binding)F: Transket_pyrECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF02779Transketolase, pyrimidine binding domain (Transket_pyr)Transketolase, pyrimidine binding domainThis family includes transketolase enzymes, pyruvate dehydrogenases, and branched chain alpha-keto acid decarboxylases.Domain
A, B
PF02780Transketolase, C-terminal domain (Transketolase_C)Transketolase, C-terminal domainThe C-terminal domain of transketolase has been proposed as a regulatory molecule binding site [2].Domain
A, B
PF00456Transketolase, thiamine diphosphate binding domain (Transketolase_N)Transketolase, thiamine diphosphate binding domainThis family includes transketolase enzymes EC:2.2.1.1. and also partially matches to 2-oxoisovalerate dehydrogenase beta subunit Swiss:P37941 EC:1.2.4.4. Both these enzymes utilise thiamine pyrophosphate as a cofactor, suggesting there may be common ...This family includes transketolase enzymes EC:2.2.1.1. and also partially matches to 2-oxoisovalerate dehydrogenase beta subunit Swiss:P37941 EC:1.2.4.4. Both these enzymes utilise thiamine pyrophosphate as a cofactor, suggesting there may be common aspects in their mechanism of catalysis.
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
Transketolase 1