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Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with inositol hexakisphosphate and Mg, presoaked with 5-IP7, Mg and Fluoride, soaking 2min in the absence of Fluoride. External Resource: Annotation Chains Type Family Name Domain Identifier Family Identifier Provenance Source (Version) A SCOP2B Superfamily Nudix 8041411 3000098 SCOP2B (2022-06-29)
Chains Family Name Domain Identifier Architecture Possible Homology Homology Topology Family Provenance Source (Version) A NUDIX e6wodA1 A: a+b two layers X: beta-Grasp H: Nudix (From Topology) T: Nudix F: NUDIX ECOD (1.6)
Chains Polymer Molecular Function Biological Process Cellular Component Diphosphoinositol polyphosphate phosphohydrolase 1 pyrophosphatase activity inositol diphosphate tetrakisphosphate diphosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity diphosphoinositol-polyphosphate diphosphatase activity hydrolase activity, acting on acid anhydrides catalytic activity bis(5'-adenosyl)-hexaphosphatase activity inositol bisdiphosphate tetrakisphosphate diphosphatase activity inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity inositol diphosphate pentakisphosphate diphosphatase activity cation binding manganese ion binding pyrophosphatase activity inositol diphosphate tetrakisphosphate diphosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity diphosphoinositol-polyphosphate diphosphatase activity hydrolase activity, acting on acid anhydrides catalytic activity bis(5'-adenosyl)-hexaphosphatase activity inositol bisdiphosphate tetrakisphosphate diphosphatase activity inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity inositol diphosphate pentakisphosphate diphosphatase activity cation binding manganese ion binding transition metal ion binding ion binding binding metal ion binding small molecule binding bis(5'-adenosyl)-pentaphosphatase activity magnesium ion binding endopolyphosphatase activity zinc ion binding 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity Less
Chains Drug Target   Associated Disease Pharos :  O95989