Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with 1,5-di-methylenebisphosphonate inositol tetrakisphosphate (1,5-PCP-IP4)
External Resource: Annotation
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
A | SCOP2B Superfamily | Nudix | 8041411 | 3000098 | SCOP2B (2022-06-29) |
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
A | NUDIX | e6wohA1 | A: a+b two layers | X: beta-Grasp | H: Nudix (From Topology) | T: Nudix | F: NUDIX | ECOD (1.6) |
Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
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| Diphosphoinositol polyphosphate phosphohydrolase 1 | - pyrophosphatase activity
- inositol diphosphate tetrakisphosphate diphosphatase activity
- hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
- hydrolase activity
- diphosphoinositol-polyphosphate diphosphatase activity
- hydrolase activity, acting on acid anhydrides
- catalytic activity
- bis(5'-adenosyl)-hexaphosphatase activity
- inositol bisdiphosphate tetrakisphosphate diphosphatase activity
- inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity
- inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity
- inositol diphosphate pentakisphosphate diphosphatase activity
- cation binding
- manganese ion binding
- pyrophosphatase activity
- inositol diphosphate tetrakisphosphate diphosphatase activity
- hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
- hydrolase activity
- diphosphoinositol-polyphosphate diphosphatase activity
- hydrolase activity, acting on acid anhydrides
- catalytic activity
- bis(5'-adenosyl)-hexaphosphatase activity
- inositol bisdiphosphate tetrakisphosphate diphosphatase activity
- inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity
- inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity
- inositol diphosphate pentakisphosphate diphosphatase activity
- cation binding
- manganese ion binding
- transition metal ion binding
- ion binding
- binding
- metal ion binding
- small molecule binding
- bis(5'-adenosyl)-pentaphosphatase activity
- magnesium ion binding
- endopolyphosphatase activity
- zinc ion binding
- 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity
- 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity
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Chains | Drug Target   | Associated Disease |
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| Pharos:  O95989 | |