6WY0
CRYSTAL STRUCTURE OF MYELOPEROXIDASE SUBFORM C (MPO) COMPLEX WITH Compound-40 A.K.A 7-[(1R)-1-phenyl-3-{[(1r,4r)-4-phenylcyclohexyl]amino}propyl]-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | An_peroxidase | e6wy0B1 | A: alpha complex topology | X: Heme-dependent peroxidases (From Topology) | H: Heme-dependent peroxidases (From Topology) | T: Heme-dependent peroxidases | F: An_peroxidase | ECOD (1.6) |
D [auth E] | An_peroxidase | e6wy0E1 | A: alpha complex topology | X: Heme-dependent peroxidases (From Topology) | H: Heme-dependent peroxidases (From Topology) | T: Heme-dependent peroxidases | F: An_peroxidase | ECOD (1.6) |
F [auth G] | An_peroxidase | e6wy0G1 | A: alpha complex topology | X: Heme-dependent peroxidases (From Topology) | H: Heme-dependent peroxidases (From Topology) | T: Heme-dependent peroxidases | F: An_peroxidase | ECOD (1.6) |
H [auth I] | An_peroxidase | e6wy0I1 | A: alpha complex topology | X: Heme-dependent peroxidases (From Topology) | H: Heme-dependent peroxidases (From Topology) | T: Heme-dependent peroxidases | F: An_peroxidase | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
B, D [auth E], F [auth G], H [auth I] | PF03098 | Animal haem peroxidase (An_peroxidase) | Animal haem peroxidase | - | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
A, C [auth D], E [auth F], G [auth H] | IPR019791 | Haem peroxidase, animal-type | Family |
A, C [auth D], E [auth F], G [auth H] | IPR037120 | Haem peroxidase domain superfamily, animal type | Homologous Superfamily |
A, C [auth D], E [auth F], G [auth H] | IPR050702 | Peroxidase/ROS_Generation | Unknown |
A, C [auth D], E [auth F], G [auth H] | IPR010255 | Haem peroxidase superfamily | Homologous Superfamily |
B, D [auth E], F [auth G], H [auth I] | IPR019791 | Haem peroxidase, animal-type | Family |
B, D [auth E], F [auth G], H [auth I] | IPR037120 | Haem peroxidase domain superfamily, animal type | Homologous Superfamily |
B, D [auth E], F [auth G], H [auth I] | IPR050702 | Peroxidase/ROS_Generation | Unknown |
B, D [auth E], F [auth G], H [auth I] | IPR010255 | Haem peroxidase superfamily | Homologous Superfamily |
Pharos: Disease Associations Pharos Homepage Annotation
Protein Modification Annotation
Modified Residue(s) | ||
---|---|---|
Chain | Residue(s) | Description |
B, D [auth E], F [auth G], H [auth I] | CSO | Parent Component: CYS :  AA0205 :  L-cysteine sulfenic acid MOD:00210 |