6ZXM
Diguanylate cyclase DgcR in complex with c-di-GMP
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | GGDEF | e6zxmA2 | A: a+b two layers | X: Alpha-beta plaits | H: Adenylyl and guanylyl cyclase catalytic domain-like | T: Adenylyl and guanylyl cyclase catalytic domain-like | F: GGDEF | ECOD (1.6) |
A | Response_reg | e6zxmA1 | A: a/b three-layered sandwiches | X: Flavodoxin-like | H: Class I glutamine amidotransferase-like | T: CheY-like | F: Response_reg | ECOD (1.6) |
C | GGDEF | e6zxmC1 | A: a+b two layers | X: Alpha-beta plaits | H: Adenylyl and guanylyl cyclase catalytic domain-like | T: Adenylyl and guanylyl cyclase catalytic domain-like | F: GGDEF | ECOD (1.6) |
C | Response_reg | e6zxmC2 | A: a/b three-layered sandwiches | X: Flavodoxin-like | H: Class I glutamine amidotransferase-like | T: CheY-like | F: Response_reg | ECOD (1.6) |
D | GGDEF | e6zxmD2 | A: a+b two layers | X: Alpha-beta plaits | H: Adenylyl and guanylyl cyclase catalytic domain-like | T: Adenylyl and guanylyl cyclase catalytic domain-like | F: GGDEF | ECOD (1.6) |
D | Response_reg | e6zxmD1 | A: a/b three-layered sandwiches | X: Flavodoxin-like | H: Class I glutamine amidotransferase-like | T: CheY-like | F: Response_reg | ECOD (1.6) |
E | GGDEF | e6zxmE2 | A: a+b two layers | X: Alpha-beta plaits | H: Adenylyl and guanylyl cyclase catalytic domain-like | T: Adenylyl and guanylyl cyclase catalytic domain-like | F: GGDEF | ECOD (1.6) |
E | Response_reg | e6zxmE1 | A: a/b three-layered sandwiches | X: Flavodoxin-like | H: Class I glutamine amidotransferase-like | T: CheY-like | F: Response_reg | ECOD (1.6) |
F | GGDEF | e6zxmF1 | A: a+b two layers | X: Alpha-beta plaits | H: Adenylyl and guanylyl cyclase catalytic domain-like | T: Adenylyl and guanylyl cyclase catalytic domain-like | F: GGDEF | ECOD (1.6) |
F | Response_reg | e6zxmF2 | A: a/b three-layered sandwiches | X: Flavodoxin-like | H: Class I glutamine amidotransferase-like | T: CheY-like | F: Response_reg | ECOD (1.6) |
B | GGDEF | e6zxmB1 | A: a+b two layers | X: Alpha-beta plaits | H: Adenylyl and guanylyl cyclase catalytic domain-like | T: Adenylyl and guanylyl cyclase catalytic domain-like | F: GGDEF | ECOD (1.6) |
B | Response_reg | e6zxmB2 | A: a/b three-layered sandwiches | X: Flavodoxin-like | H: Class I glutamine amidotransferase-like | T: CheY-like | F: Response_reg | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00072 | Response regulator receiver domain (Response_reg) | Response regulator receiver domain | This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain. | Domain | |
PF00990 | Diguanylate cyclase, GGDEF domain (GGDEF) | Diguanylate cyclase, GGDEF domain | This domain is found linked to a wide range of non-homologous domains in a variety of bacteria. It has been shown to be homologous to the adenylyl cyclase catalytic domain [1] and has diguanylate cyclase activity [4]. This observation correlates with ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR011006 | CheY-like superfamily | Homologous Superfamily | |
IPR050469 | Bacterial Diguanylate Cyclase | Family | |
IPR000160 | GGDEF domain | Domain | |
IPR001789 | Signal transduction response regulator, receiver domain | Domain | |
IPR043128 | Reverse transcriptase/Diguanylate cyclase domain | Homologous Superfamily | |
IPR029787 | Nucleotide cyclase | Homologous Superfamily |