6AU6
Crystal structure of GDP-bound human GNAS R201C mutant
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | G-alpha | e6au6A2 | A: alpha arrays | X: Transducin (alpha subunit), insertion domain (From Topology) | H: Transducin (alpha subunit), insertion domain (From Topology) | T: Transducin (alpha subunit), insertion domain | F: G-alpha | ECOD (1.6) |
A | Ras | e6au6A1 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: Ras | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.40.50.300 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | P-loop containing nucleotide triphosphate hydrolases | CATH (4.3.0) |
A | 1.10.400.10 | Mainly Alpha | Orthogonal Bundle | GI Alpha 1, domain 2-like | GI Alpha 1, domain 2-like | CATH (4.3.0) |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR001019 | Guanine nucleotide binding protein (G-protein), alpha subunit | Family | |
IPR011025 | G protein alpha subunit, helical insertion | Homologous Superfamily | |
IPR027417 | P-loop containing nucleoside triphosphate hydrolase | Homologous Superfamily | |
IPR000367 | G-protein alpha subunit, group S | Family |