Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad6gvaa_ Alpha and beta proteins (a+b) Protein kinase-like (PK-like) Protein kinase-like (PK-like) Protein kinases, catalytic subunit Cyclin-dependent PK, CDK2 Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Bd6gvab1 All alpha proteins Cyclin-like Cyclin-like Cyclin Cyclin A Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyProtein kinase-like (PK-like) 8040310 3000066 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyCyclin-like 8038664 3000768 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyCyclin-like 8038665 3000768 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APkinase_Tyre6gvaA1 A: a+b complex topologyX: Protein kinase/SAICAR synthase/ATP-grasp (From Homology)H: Protein kinase/SAICAR synthase/ATP-graspT: Protein kinaseF: Pkinase_TyrECOD (1.6)
BCyclin_Ce6gvaB2 A: alpha arraysX: HTHH: HTHT: Cyclin-likeF: Cyclin_CECOD (1.6)
BCyclin_Ne6gvaB1 A: alpha arraysX: HTHH: HTHT: Cyclin-likeF: Cyclin_NECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
B1.10.472.10 Mainly Alpha Orthogonal Bundle Cyclin A domain 1CATH (utative)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF00069Protein kinase domain (Pkinase)Protein kinase domain- Domain
PF02984Cyclin, C-terminal domain (Cyclin_C)Cyclin, C-terminal domainCyclins regulate cyclin dependent kinases (CDKs). Swiss:P22674 is a Uracil-DNA glycosylase that is related to other cyclins [4]. Cyclins contain two domains of similar all-alpha fold, of which this family corresponds with the C-terminal domain.Domain
PF00134Cyclin, N-terminal domain (Cyclin_N)Cyclin, N-terminal domainCyclins regulate cyclin dependent kinases (CDKs). Swiss:P22674 is a Uracil-DNA glycosylase that is related to other cyclins [4]. Cyclins contain two domains of similar all-alpha fold, of which this family corresponds with the N-terminal domain.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Cyclin-dependent kinase 2
Cyclin-A2

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
PharosP24941
PharosP20248

Protein Modification Annotation

Modified Residue(s)
ChainResidue(s)Description
TPO Parent Component: THR

RESIDAA0038

PSI-MOD :  O-phospho-L-threonine MOD:00047