Annotations: 6P2D

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Ribokinase-like	8093865	4000759	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Ribokinase-like	8093866	3001268	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PfkB	e6p2dA1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Ribokinase-like (From Topology)	T: Ribokinase-like	F: PfkB	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.1190.20	Alpha Beta	3-Layer(aba) Sandwich	UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase	Ribokinase	CATH (utative)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00294	pfkB family carbohydrate kinase (PfkB)	pfkB family carbohydrate kinase	This family includes a variety of carbohydrate and pyrimidine kinases.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Ketohexokinase	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding carbohydrate kinase activity kinase activity ketohexokinase activity transferase activity catalytic activity phosphotransferase activity, alcohol group as acceptor transferase activity, transferring phosphorus-containing groups	response to stimulus response to metal ion response to chemical response to zinc ion monosaccharide metabolic process carbohydrate metabolic process hexose metabolic process small molecule metabolic process metabolic process primary metabolic process fructose metabolic process response to hormone response to endogenous stimulus response to peptide hormone response to stimulus response to metal ion response to chemical response to zinc ion monosaccharide metabolic process carbohydrate metabolic process hexose metabolic process small molecule metabolic process metabolic process primary metabolic process fructose metabolic process response to hormone response to endogenous stimulus response to peptide hormone response to insulin response to oxygen-containing compound response to nitrogen compound catabolic process fructose catabolic process hexose catabolic process cellular metabolic process carbohydrate catabolic process carbohydrate derivative metabolic process glyceraldehyde-3-phosphate metabolic process organophosphate metabolic process cellular aldehyde metabolic process phosphate-containing compound metabolic process cellular process phosphorus metabolic process monosaccharide catabolic process small molecule catabolic process fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate regulation of cellular process energy derivation by oxidation of organic compounds regulation of generation of precursor metabolites and energy regulation of polysaccharide metabolic process regulation of primary metabolic process glucan metabolic process polysaccharide metabolic process regulation of carbohydrate metabolic process regulation of biological process glycogen metabolic process biological regulation regulation of cellular metabolic process generation of precursor metabolites and energy regulation of macromolecule metabolic process energy reserve metabolic process macromolecule metabolic process regulation of glycogen metabolic process regulation of metabolic process response to hexose response to monosaccharide response to carbohydrate response to fructose response to glucose response to sucrose response to disaccharide ribonucleotide catabolic process pyridine nucleotide catabolic process oxoacid metabolic process organophosphate catabolic process nucleoside phosphate catabolic process organic acid metabolic process glycolytic process through fructose-1-phosphate nucleobase-containing compound metabolic process glycolytic process pyridine-containing compound metabolic process purine ribonucleotide catabolic process pyridine nucleotide metabolic process nucleoside phosphate metabolic process nicotinamide nucleotide metabolic process pyruvate metabolic process purine nucleoside diphosphate metabolic process purine-containing compound catabolic process nucleotide metabolic process nucleobase-containing compound catabolic process nucleoside diphosphate metabolic process purine nucleoside diphosphate catabolic process nucleoside diphosphate catabolic process nucleoside triphosphate metabolic process monocarboxylic acid metabolic process purine ribonucleotide metabolic process pyridine-containing compound catabolic process ribose phosphate metabolic process ATP metabolic process purine nucleotide metabolic process ribonucleotide metabolic process nucleobase-containing small molecule metabolic process purine ribonucleoside triphosphate metabolic process ribonucleoside diphosphate metabolic process ribonucleoside diphosphate catabolic process nucleotide catabolic process ribonucleoside triphosphate metabolic process purine nucleoside triphosphate metabolic process purine nucleotide catabolic process carbohydrate derivative catabolic process ADP catabolic process carboxylic acid metabolic process purine-containing compound metabolic process ADP metabolic process purine ribonucleoside diphosphate metabolic process purine ribonucleoside diphosphate catabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol membrane-bounded organelle intracellular organelle organelle nucleus intracellular membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR034093	Ketohexokinase	Family
A	IPR011611	Carbohydrate kinase PfkB	Domain
A	IPR052562	Ketohexokinase-related	Family
A	IPR029056	Ribokinase-like	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.