Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad6q9oa_ All alpha proteins SWIB/MDM2 domain SWIB/MDM2 domain SWIB/MDM2 domain MDM2 Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Bd6q9ob_ All alpha proteins SWIB/MDM2 domain SWIB/MDM2 domain SWIB/MDM2 domain MDM2 Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilySWIB/MDM2 domain-like 8037458 3000287 SCOP2B (2022-06-29)
BSCOP2B SuperfamilySWIB/MDM2 domain-like 8037458 3000287 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ASWIBe6q9oA1 A: alpha arraysX: SWIB/MDM2 domain (From Topology)H: SWIB/MDM2 domain (From Topology)T: SWIB/MDM2 domainF: SWIBECOD (1.6)
BSWIBe6q9oB1 A: alpha arraysX: SWIB/MDM2 domain (From Topology)H: SWIB/MDM2 domain (From Topology)T: SWIB/MDM2 domainF: SWIBECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A1.10.245.10 Mainly Alpha Orthogonal Bundle MDM2 SWIB/MDM2 domainCATH (utative)
B1.10.245.10 Mainly Alpha Orthogonal Bundle MDM2 SWIB/MDM2 domainCATH (utative)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF02201SWIB/MDM2 domain (SWIB)SWIB/MDM2 domainThis family includes the SWIB domain and the MDM2 domain [1]. The p53-associated protein (MDM2) is an inhibitor of the p53 tumour suppressor gene binding the transactivation domain and down regulating the ability of p53 to activate transcription. Thi ...This family includes the SWIB domain and the MDM2 domain [1]. The p53-associated protein (MDM2) is an inhibitor of the p53 tumour suppressor gene binding the transactivation domain and down regulating the ability of p53 to activate transcription. This family contains the p53 binding domain of MDM2 [2].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
E3 ubiquitin-protein ligase Mdm2