Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ADNA_primase_Se6sa0A1 A: a+b complex topologyX: Prim-pol domain (From Topology)H: Prim-pol domain (From Topology)T: Prim-pol domainF: DNA_primase_SECOD (1.6)
E [auth D]DNA_primase_Se6sa0D1 A: a+b complex topologyX: Prim-pol domain (From Topology)H: Prim-pol domain (From Topology)T: Prim-pol domainF: DNA_primase_SECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A,
E [auth D]
PF21686LigD, primase-polymerase domain (LigD_Prim-Pol)LigD, primase-polymerase domainThis entry represents the primase-polymerase domain (Prim-Pol) of bacterial LigD proteins, such as LigD from Pseudomonas aeruginosa and Mycobacterium tuberculosis. LigD, together with Ku protein, is required for nonhomologous end-joining (NHEJ)-media ...This entry represents the primase-polymerase domain (Prim-Pol) of bacterial LigD proteins, such as LigD from Pseudomonas aeruginosa and Mycobacterium tuberculosis. LigD, together with Ku protein, is required for nonhomologous end-joining (NHEJ)-mediated repair of DNA double-strand breaks (DSB). This domain belongs to the archaeal/eukaryal primase (AEP) superfamily and mediates several nucleotidyl transferase activities, including DNA-dependent RNA primase, terminal transferase and DNA-dependent DNA/RNA gap-filling polymerase activities [1-5].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A,
E [auth D]
DNA polymerase LigD, polymerase domain - -
B,
F [auth E]
DNA (5'-D(P*GP*CP*GP*AP*GP*CP*G)-3')---
C,
G [auth F]
DNA (5'-D(*CP*GP*CP*TP*CP*GP*CP*AP*AP*CP*GP*CP*A)-3')---
D [auth H],
H [auth G]
DNA (5'-D(P*TP*GP*CP*GP)-3')---