Annotations: 7AUI

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	NUDIX_1	e7auiA1	A: a+b two layers	X: beta-Grasp	H: Nudix (From Topology)	T: Nudix	F: NUDIX_1	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00293	NUDIX domain (NUDIX)	NUDIX domain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Diphosphoinositol polyphosphate phosphohydrolase DDP1	phosphodiesterase decapping endonuclease activity endonuclease activity RNA endonuclease activity, producing 5'-phosphomonoesters catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity hydrolase activity nuclease activity hydrolase activity, acting on ester bonds RNA endonuclease activity endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters catalytic activity pyrophosphatase activity bis(5'-adenosyl)-hexaphosphatase activity phosphodiesterase decapping endonuclease activity endonuclease activity RNA endonuclease activity, producing 5'-phosphomonoesters catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity hydrolase activity nuclease activity hydrolase activity, acting on ester bonds RNA endonuclease activity endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters catalytic activity pyrophosphatase activity bis(5'-adenosyl)-hexaphosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity, acting on acid anhydrides endopolyphosphatase activity bis(5'-adenosyl)-pentaphosphatase activity diphosphoinositol-polyphosphate diphosphatase activity cation binding ion binding binding metal ion binding small molecule binding	nucleoside phosphate metabolic process catabolic process organophosphate catabolic process primary metabolic process diadenosine polyphosphate metabolic process nucleoside phosphate catabolic process nucleotide metabolic process nucleobase-containing compound catabolic process nucleobase-containing compound metabolic process diadenosine hexaphosphate metabolic process organophosphate metabolic process diadenosine polyphosphate catabolic process nucleobase-containing small molecule metabolic process phosphate-containing compound metabolic process nucleoside phosphate metabolic process catabolic process organophosphate catabolic process primary metabolic process diadenosine polyphosphate metabolic process nucleoside phosphate catabolic process nucleotide metabolic process nucleobase-containing compound catabolic process nucleobase-containing compound metabolic process diadenosine hexaphosphate metabolic process organophosphate metabolic process diadenosine polyphosphate catabolic process nucleobase-containing small molecule metabolic process phosphate-containing compound metabolic process metabolic process cellular process small molecule metabolic process phosphorus metabolic process nucleotide catabolic process diadenosine hexaphosphate catabolic process polyol metabolic process organic hydroxy compound metabolic process alcohol metabolic process inositol phosphate metabolic process diphosphoinositol polyphosphate metabolic process cellular catabolic process oxoacid metabolic process organic acid metabolic process polyphosphate catabolic process polyphosphate metabolic process diadenosine pentaphosphate metabolic process diadenosine pentaphosphate catabolic process ribose phosphate metabolic process ribonucleotide catabolic process carbohydrate derivative metabolic process purine nucleotide metabolic process ribonucleotide metabolic process purine ribonucleotide catabolic process purine nucleotide catabolic process carbohydrate derivative catabolic process adenosine 5'-(hexahydrogen pentaphosphate) catabolic process purine-containing compound catabolic process purine-containing compound metabolic process adenosine 5'-(hexahydrogen pentaphosphate) metabolic process purine ribonucleotide metabolic process	cellular anatomical structure intracellular anatomical structure cytoplasm membrane-bounded organelle intracellular organelle organelle nucleus intracellular membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR047198	Diphosphoinositol polyphosphate phosphohydrolase-like, NUDIX domain	Domain
A	IPR000086	NUDIX hydrolase domain	Domain
A	IPR015797	NUDIX hydrolase-like domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.