7D6Y
eIF4E in Complex with a Disulphide-Free Autonomous VH Domain
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | IF4E | e7d6yA1 | A: a+b two layers | X: Translation initiation factor eIF4e and phosphothreonine lyase (From Topology) | H: Translation initiation factor eIF4e and phosphothreonine lyase (From Topology) | T: Translation initiation factor eIF4e and phosphothreonine lyase | F: IF4E | ECOD (1.6) |
B | V-set_12 | e7d6yB1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set_12 | ECOD (1.6) |
SAbDab Antibody Annotation SAbDab Database Homepage
Chain | Chain Class | Chain Subclass | Chain Type | Antigen Name(s) | Provenance Source |
---|---|---|---|---|---|
Heavy Chain | IGHV3 | - | eukaryotic translation initiation factor 4e | SAbDab (2024-11-08) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF01652 | Eukaryotic initiation factor 4E (IF4E) | Eukaryotic initiation factor 4E | - | Domain | |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR023398 | Translation Initiation factor eIF- 4e-like | Homologous Superfamily | |
IPR019770 | Eukaryotic translation initiation factor 4E (eIF-4E), conserved site | Conserved Site | |
IPR001040 | Translation Initiation factor eIF- 4e | Family |