7N7B

crystal structure of the N-formyltrasferase HCAN_0200 from Helicobacter canadensis on complex with folinic acid and dTDP-3-aminofucose

External Resource: Annotation


Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AFormyl_trans_C_1e7n7bA2 A: beta barrelsX: FMT C-terminal domain-likeH: FMT C-terminal domain-related (From Topology)T: FMT C-terminal domain-relatedF: Formyl_trans_C_1ECOD (1.6)
AFormyl_trans_Ne7n7bA1 A: a/b three-layered sandwichesX: Formyltransferase (From Topology)H: Formyltransferase (From Topology)T: FormyltransferaseF: Formyl_trans_NECOD (1.6)
BFormyl_trans_C_1e7n7bB1 A: beta barrelsX: FMT C-terminal domain-likeH: FMT C-terminal domain-related (From Topology)T: FMT C-terminal domain-relatedF: Formyl_trans_C_1ECOD (1.6)
BFormyl_trans_Ne7n7bB2 A: a/b three-layered sandwichesX: Formyltransferase (From Topology)H: Formyltransferase (From Topology)T: FormyltransferaseF: Formyl_trans_NECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF00551Formyl transferase (Formyl_trans_N)Formyl transferaseThis family includes the following members. Glycinamide ribonucleotide transformylase catalyses the third step in de novo purine biosynthesis, the transfer of a formyl group to 5'-phosphoribosylglycinamide. Formyltetrahydrofolate deformylase produces ...This family includes the following members. Glycinamide ribonucleotide transformylase catalyses the third step in de novo purine biosynthesis, the transfer of a formyl group to 5'-phosphoribosylglycinamide. Formyltetrahydrofolate deformylase produces formate from formyl- tetrahydrofolate. Methionyl-tRNA formyltransferase transfers a formyl group onto the amino terminus of the acyl moiety of the methionyl aminoacyl-tRNA. Inclusion of the following members is supported by PSI-blast. HOXX_BRAJA (P31907) contains a related domain of unknown function. PRTH_PORGI (P46071) contains a related domain of unknown function. Y09P_MYCTU (Q50721) contains a related domain of unknown function.
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
Formyl_trans_N domain-containing protein - -

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B
IPR002376Formyl transferase, N-terminalDomain
A, B
IPR036477Formyl transferase, N-terminal domain superfamilyHomologous Superfamily