7PQ6

Crystal Structure of the Ring Nuclease 0811 mutant-S12A from Sulfolobus islandicus (Sis0811)


Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
A [auth AAA]COG4006e7pq6AAA2 A: alpha arraysX: HTHH: HTHT: wingedF: COG4006ECOD (1.6)
A [auth AAA]Cas_APE2256e7pq6AAA1 A: a/b three-layered sandwichesX: CARF (CRISPR-associated Rossmann fold) domains (From Topology)H: CARF (CRISPR-associated Rossmann fold) domains (From Topology)T: CARF (CRISPR-associated Rossmann fold) domainsF: Cas_APE2256ECOD (1.6)
B [auth BBB]COG4006e7pq6BBB2 A: alpha arraysX: HTHH: HTHT: wingedF: COG4006ECOD (1.6)
B [auth BBB]Cas_APE2256e7pq6BBB1 A: a/b three-layered sandwichesX: CARF (CRISPR-associated Rossmann fold) domains (From Topology)H: CARF (CRISPR-associated Rossmann fold) domains (From Topology)T: CARF (CRISPR-associated Rossmann fold) domainsF: Cas_APE2256ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A [auth AAA],
B [auth BBB]
PF22165SSO1393-like, winged-helix domain (SSO1393-like_WHD)SSO1393-like, winged-helix domainThis entry represents a WH-like domain present in SSO1393-like proteins. SSO1393 is an archaeal protein from Sulfolobus solfataricus (PDB:3qyf). This protein has been described as a component of the CRISPR system [1]. CRISPR (clustered regularly inte ...This entry represents a WH-like domain present in SSO1393-like proteins. SSO1393 is an archaeal protein from Sulfolobus solfataricus (PDB:3qyf). This protein has been described as a component of the CRISPR system [1]. CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids) [1,2].
Domain
A [auth AAA],
B [auth BBB]
PF09651CRISPR-associated protein (Cas_APE2256) (Cas_APE2256)CRISPR-associated protein (Cas_APE2256)- Family