7Q9U
Crystal structure of the high affinity KRas mutant PDE6D complex
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A [auth AAA] | SCOP2B Superfamily | Ras-like P-loop GTPases | 8060856 | 3002022 | SCOP2B (2022-06-29) |
B [auth BBB] | SCOP2B Superfamily | Ras-like P-loop GTPases | 8060856 | 3002022 | SCOP2B (2022-06-29) |
C [auth DDD] | SCOP2B Superfamily | E set domains | 8055021 | 3000070 | SCOP2B (2022-06-29) |
D [auth CCC] | SCOP2B Superfamily | E set domains | 8055021 | 3000070 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A [auth AAA] | Ras | e7q9uAAA1 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: Ras | ECOD (1.6) |
B [auth BBB] | Ras | e7q9uBBB1 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: Ras | ECOD (1.6) |
C [auth DDD] | GMP_PDE_delta | e7q9uDDD1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: GMP_PDE_delta | ECOD (1.6) |
D [auth CCC] | GMP_PDE_delta | e7q9uCCC1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: GMP_PDE_delta | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A [auth AAA], B [auth BBB] | PF00071 | Ras family (Ras) | Ras family | Includes sub-families Ras, Rab, Rac, Ral, Ran, Rap Ypt1 and more. Shares P-loop motif with GTP_EFTU, arf and myosin_head. See Pfam:PF00009 Pfam:PF00025, Pfam:PF00063. As regards Rab GTPases, these are important regulators of vesicle formation, motil ... | Domain |
C [auth DDD], D [auth CCC] | PF05351 | GMP-PDE, delta subunit (GMP_PDE_delta) | GMP-PDE, delta subunit | - | Family |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Pharos: Disease Associations Pharos Homepage Annotation
Protein Modification Annotation
Modified Residue(s) | ||
---|---|---|
Chain | Residue(s) | Description |
A [auth AAA], B [auth BBB] | CMT | Parent Component: CYS :  AA0105 :  L-cysteine methyl ester MOD:00114 |