7T3V

Metal dependent activation of Plasmodium falciparum M17 aminopeptidase, spacegroup P22121 after crystals soaked with Zn2+


Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APeptidase_M17e7t3vA2 A: a/b three-layered sandwichesX: Phosphorylase/hydrolase-likeH: Zn-dependent exopeptidases (From Topology)T: Zn-dependent exopeptidasesF: Peptidase_M17ECOD (1.6)
APeptidase_M17_Ne7t3vA1 A: a/b three-layered sandwichesX: Macro domain-like (From Topology)H: Macro domain-like (From Topology)T: Macro domain-likeF: Peptidase_M17_NECOD (1.6)
BPeptidase_M17e7t3vB2 A: a/b three-layered sandwichesX: Phosphorylase/hydrolase-likeH: Zn-dependent exopeptidases (From Topology)T: Zn-dependent exopeptidasesF: Peptidase_M17ECOD (1.6)
BPeptidase_M17_Ne7t3vB1 A: a/b three-layered sandwichesX: Macro domain-like (From Topology)H: Macro domain-like (From Topology)T: Macro domain-likeF: Peptidase_M17_NECOD (1.6)
CPeptidase_M17e7t3vC1 A: a/b three-layered sandwichesX: Phosphorylase/hydrolase-likeH: Zn-dependent exopeptidases (From Topology)T: Zn-dependent exopeptidasesF: Peptidase_M17ECOD (1.6)
CPeptidase_M17_Ne7t3vC2 A: a/b three-layered sandwichesX: Macro domain-like (From Topology)H: Macro domain-like (From Topology)T: Macro domain-likeF: Peptidase_M17_NECOD (1.6)
DPeptidase_M17e7t3vD2 A: a/b three-layered sandwichesX: Phosphorylase/hydrolase-likeH: Zn-dependent exopeptidases (From Topology)T: Zn-dependent exopeptidasesF: Peptidase_M17ECOD (1.6)
DPeptidase_M17_Ne7t3vD1 A: a/b three-layered sandwichesX: Macro domain-like (From Topology)H: Macro domain-like (From Topology)T: Macro domain-likeF: Peptidase_M17_NECOD (1.6)
EPeptidase_M17e7t3vE1 A: a/b three-layered sandwichesX: Phosphorylase/hydrolase-likeH: Zn-dependent exopeptidases (From Topology)T: Zn-dependent exopeptidasesF: Peptidase_M17ECOD (1.6)
EPeptidase_M17_Ne7t3vE2 A: a/b three-layered sandwichesX: Macro domain-like (From Topology)H: Macro domain-like (From Topology)T: Macro domain-likeF: Peptidase_M17_NECOD (1.6)
FPeptidase_M17e7t3vF2 A: a/b three-layered sandwichesX: Phosphorylase/hydrolase-likeH: Zn-dependent exopeptidases (From Topology)T: Zn-dependent exopeptidasesF: Peptidase_M17ECOD (1.6)
FPeptidase_M17_Ne7t3vF1 A: a/b three-layered sandwichesX: Macro domain-like (From Topology)H: Macro domain-like (From Topology)T: Macro domain-likeF: Peptidase_M17_NECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D, E
PF00883Cytosol aminopeptidase family, catalytic domain (Peptidase_M17)Cytosol aminopeptidase family, catalytic domainThe two associated zinc ions and the active site are entirely enclosed within the C-terminal catalytic domain in leucine aminopeptidase.Domain

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D, E
IPR000819Peptidase M17, leucyl aminopeptidase, C-terminalDomain
A, B, C, D, E
IPR011356Peptidase M17, leucine aminopeptidase/peptidase BFamily
A, B, C, D, E
IPR043472Macro domain-likeHomologous Superfamily
A, B, C, D, E
IPR023042Peptidase M17, leucine aminopeptidaseFamily